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Are antidepressants safe during pregnancy?

  • Anto P. Rajkumar (a1) and K. S. Jacob (a1)
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1 Ramos, E, St-André, M, Rey, E, Oraichi, D, Bérard, A. Duration of antidepressant use during pregnancy and risk of major congenital malformations. Br J Psychiatry 2008; 192: 344–50.
2 Hemels, ME, Einarson, A, Koren, G, Lanctôt, KL, Einarson, TR. Antidepressant use during pregnancy and the rates of spontaneous abortions: a meta-analysis. Ann Pharmacother 2005; 39: 803–9.
3 Pastuszak, A, Schick-Boschetto, B, Zuber, C, Feldkamp, M, Pinelli, M, Sihn, S, Donnenfeld, A, McCormack, M, Leen-Mitchell, M, Woodland, C. Pregnancy outcome following first-trimester exposure to fluoxetine (Prozac). JAMA 1993; 269: 2246–8.
4 Djulus, J, Koren, G, Einarson, TR, Wilton, L, Shakir, S, Diav-Citrin, O, Kennedy, D, Voyer Lavigne, S, De Santis, M, Einarson, A. Exposure to mirtazapine during pregnancy: a prospective, comparative study of birth outcomes. J Clin Psychiatry 2006; 67: 1280–4.
5 Chun-Fai-Chan, B, Koren, G, Fayez, I, Kalra, S, Voyer-Lavigne, S, Boshier, A, Shakir, S, Einarson, A. Pregnancy outcome of women exposed to bupropion during pregnancy: a prospective comparative study. Am J Obstet Gynecol 2005; 192: 932–6.
6 Chambers, C, Johnson, K, Dick, L, Felix, R, Jones, KL. Birth outcomes in pregnant women taking fluoxetine. N Engl J Med 1996; 335: 1010–5.

Are antidepressants safe during pregnancy?

  • Anto P. Rajkumar (a1) and K. S. Jacob (a1)

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