Hostname: page-component-848d4c4894-2xdlg Total loading time: 0 Render date: 2024-06-21T16:56:52.906Z Has data issue: false hasContentIssue false

Delineation of thalamic nuclei immunoreactive for calcium-binding proteins in and around the posterior pole of the ventral posterior complex

Published online by Cambridge University Press:  12 April 2006

Edward Jones
Affiliation:
Center for Neuroscience, University of California, 1544 Newton Court, Davis, CA 95616, USA
Kristyna Lensky
Affiliation:
Center for Neuroscience, University of California, 1544 Newton Court, Davis, CA 95616, USA
Victor Chan
Affiliation:
Center for Neuroscience, University of California, 1544 Newton Court, Davis, CA 95616, USA

Abstract

An atlas of serial sections stained alternately for one of the three calcium-binding proteins, calbindin, calretinin or parvalbumin, or for markers that demarcate borders of thalamic nuclei in and around the posterior pole of the ventral posterior thalamic nucleus of a macaque monkey is presented. The concentrated focal zone of calbindin-immunoreactive fiber ramifications considered by others to form a specific pain and temperature relay nucleus is shown to be located entirely within the confines of the ventral posterior medial (VPM) nucleus. It contains a large population of calbindin-immunoreactive cells and overlaps a region of dense cell and fiber immunoreactivity for parvalbumin. In other parts of the ventral posterior complex, calbindin and parvalbumin immunoreactivity is complementary rather than co-extensive. It is unlikely that the zone of intense calbindin immunoreactivity in VPM forms the only thalamic relay for noxious thermal and mechanical inputs to the cerebral cortex.

Type
Research Article
Copyright
2001 Elsevier Science Ltd

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)