Skip to main content Accessibility help
×
Home

Congenital and acquired bleeding problems in elderly patients

  • AL Nicolle (a1), KL Talks (a2) and JP Hanley (a2)

Extract

Bleeding in elderly patients is most commonly due to an underlying structural problem or an acquired coagulopathy. Occasionally, previously asymptomatic congenital bleeding disorders may present at an advanced age. When considering the possible causes of a clinical bleeding problem, the coagulation cascade is still a good starting-point. However, it is important to realize that the traditional model of the coagulation cascade has been superceded by the concept of a ‘coagulation network’. This updated model recognizes the importance of tissue factor in the initiation of coagulation. Despite the complexity of this model, the basic coagulation tests can still be interpreted in relation to the ‘intrinsic’, ‘extrinsic’ and ‘final common pathway’ components of the old-fashioned cascade (Figure 1).

Copyright

Corresponding author

Address for correspondence: JP Hanley, Department of Haematology, Newcastle Hospitals NHS Trust, Royal Victoria Infirmary, Queen Victoria Road, Newcastle-upon-Tyne, NE1 4LP, UK.

Related content

Powered by UNSILO

Congenital and acquired bleeding problems in elderly patients

  • AL Nicolle (a1), KL Talks (a2) and JP Hanley (a2)

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed.