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The CFTR gene: male infertility and assisted conception

Published online by Cambridge University Press:  01 July 1999

S Kulshrestha ,
A Makrigiannakis  and
P Patrizio
S Kulshrestha
Affiliation:
Hospital of the University of Pennsylvania, Division of Human Reproduction, Philadelphia, USA
A Makrigiannakis
Affiliation:
Hospital of the University of Pennsylvania, Division of Human Reproduction, Philadelphia, USA
P Patrizio
Affiliation:
Hospital of the University of Pennsylvania, Division of Human Reproduction, Philadelphia, USA
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Abstract

Approximately 30–40% of couples seeking fertility treatments have male factor infertility. Their dysfunctions include azoospermia, oligozoospermia, asthenozoospermia and teratozoospermia. Those with azoospermia represent about 25% of the total, and of these about 30% have an obstructive process while the remaining have either primary or secondary testicular failure. In the obstructive azoospermia group, 25% of males have congenital bilateral absence of the vas deferens (CBAVD).

Type
Research Article
Information
Reproductive Medicine Review , Volume 7 , Issue 2 , July 1999 , pp. 155 - 160
Copyright
© 1999 Cambridge University Press

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