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Pharmacokinetics of gonadotropin therapy

Published online by Cambridge University Press:  03 June 2009

Tally Levy
Affiliation:
Department of Obstetrics and Gynecology, Golda Medical Center, (Hasharon Hospital), Petah Tikva, and Sackler School of Medicine, Tel Aviv University, Israel
Zion Ben-Rafael
Affiliation:
Department of Obstetrics and Gynecology, Golda Medical Center, (Hasharon Hospital), Petah Tikva, and Sackler School of Medicine, Tel Aviv University, Israel
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Extract

Ovulation is the result of an integrated action of the hypothalamus, pituitary and ovaries. During the process, gonadal steroids, peptides and growth factors are produced and influence the synthesis and release of gonadotropin-releasing hormone (GnRH), follicle stimulating hormone (FSH) and luteinizing hormone (LH). These latter compounds play a crucial role in folliculogenesis and are frequently used in the management of infertility.

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Articles
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Copyright © Cambridge University Press 1996

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