Azzam, E.I., De Toledo, S.M., Spitz, D.R., Little, J.B. (2002) Oxidative metabolism modulates signal transduction and micronucleus formation in bystander cells from alpha-particle-irradiated normal human fibroblast cultures, Cancer Res. 62, 5436-5442.
Azzam, E.I., De Toledo, S.M., Little, J.B. (2003) Oxidative metabolism, gap junctions and the ionizing radiation-induced bystander effect, Oncogene 13, 7050-7057.
Balcer-Kubiczek, E.K., Harrison, G.H., Xu, J.F., Gutierrez, P.L. (2002) Coordinate late expression of trefoil peptide genes (pS2/TFF1 and ITF/TFF3) in human breast, colon, and gastric tumor cells exposed to X-rays, Mol. Cancer Ther. 6, 405-415.
Barcellos-Hoff, M.H., Brooks, A.L. (2001) Extracellular signaling through the microenvironment: a hypothesis relating carcinogenesis, bystander effects, and genomic instability, Radiat. Res. 156, 618-627.
Baverstock, K. (2000) Radiation-induced genomic instability: a paradigm-breaking phenomenon and its relevance to environmentally induced cancer, Mutat. Res. 254, 89-109.
Belyakov, O.V., Folkard, M., Mothersill, C., Prise, K.M., Michael, B.D. (2002) Bystander-induced apoptosis and premature differentiation in primary urothelial explants after charged particle microbeam irradiation, Radiat. Prot. Dosim. 99, 249-251.
Belyakov, O.V., Folkard, M., Mothersill, C., Prise, K.M., Michael, B.D. (2003) A proliferation-dependent bystander effect in primary porcine and human urothelial explants in response to targeted irradiation, Br. J. Cancer. 88, 767-774.
Bishayee, A., Hill, H.Z., Stein, D., Rao, D.V., Howell, R.W. (2001) Free radical-initiated and gap junction-mediated bystander effect due to nonuniform distribution of incorporated radioactivity in a three-dimensional tissue culture model, Radiat. Res. 155, 335-44.
Burlakova, E.B., Mikhailov, V.F., Azurik, V.K. (2001) The redox homeostasis system in radiation-induced genomic instability, Radiat. Biol. Radioecol. 41, 489-499.
Calabrese, E.J., Baldwin, L.A. (2001a) The frequency of U-shaped dose responses in the toxicological literature, Toxicol. Sci. 62, 330-338.
Calabrese, E.J., Baldwin, L.A. (2001b) Hormesis: U-shaped dose responses and their centrality in toxicology, Trends Pharmacol. Sci. 22, 285-291.
Calabrese, E.J., Baldwin, L.A. (2002) Applications of hormesis in toxicology, risk assessment and chemotherapeutics, Trends Pharmacol. Sci. 23, 331-337.
Coates, P.J., Lorimore, S.A., Lindsay, K.J., Wright, E.G. (2003) Tissue-specific p53 responses to ionizing radiation and their genetic modification: the key to tissue-specific tumour susceptibility?, J. Pathol. 201, 377-388.
Coen, N., Mothersill, C., Kadhim, M., Wright, E.G. (2001) Heavy metals of relevance to human health induce genomic instability, J. Pathol. 195, 293-299.
Davies, M.J. (2003) Singlet oxygen-mediated damage to proteins and its consequences, Biochem. Biophys. Res. Commun. 305, 61-70.
Dent, P., Yacoub, A., Fisher, P.B., Hagan, M.P., Grant, S. (2003) MAPK pathways in radiation responses, Oncogene. 22, 5885-5896.
Emerit, I., Oganesian, N., Arutyunian, R., Pogossian, A., Sarkisian, T., Cernjavski, L., Levy, A., Feingold, J. (1997) Oxidative stress-related clastogenic factors in plasma from Chernobyl liquidators: protective effects of antioxidant plant phenols, vitamins and oligoelements, Mutat. Res. 377, 239-246.
Erickson, A.C., Barcellos-Hoff, M.H. (2003) The not-so innocent bystander: the microenvironment as a therapeutic target in cancer, Expert. Opin. Ther. Targ. 7, 71-88
Faguet, G.B., Reichard, S.M., Welter, D.A. (1984) Radiation-induced clastogenic plasma factors, Cancer Genet. Cytogenet. 12, 73-83.
Geard, C.R., Jenkins-Baker, G., Marino, S.A., Ponnaiya.B. (2002) Novel approaches with track segment alpha particles and cell co-cultures in studies of bystander effects, Radiat. Prot. Dosim. 99, 233-236.
Gerashchenko, B.I., Howell, R.W. (2003) Cell proximity is a prerequisite for the proliferative response of bystander cells co-cultured with cells irradiated with gamma-rays, Cytometry 56A, 71-80.
Iyer, R., Lehnert, B.E. (2002a) Low dose, low-LET ionizing radiation-induced radioadaptation and associated early responses in unirradiated cells, Mutat. Res. 503, 1-9.
Iyer, R., Lehnert, B.E. (2002b) Alpha-particle-induced increases in the radioresistance of normal human bystander cells, Radiat. Res. 157, 3-7.
Keyes E., Howe O., Seymour C.B., Lyng F., Mothersill C. (2005) Prolonged expression of delayed cell death in the progeny of cells exposed to direct irradiation or to culture medium from irradiated cells, Int. J. Radiat. Biol. (being revised).
Lehnert, B.E., Iyer, R. (2002) Exposure to low-level chemicals and ionizing radiation: reactive oxygen species and cellular pathways, Hum. Exp. Toxicol. 21, 65-69.
Limoli, C.L., Giedzinski, E. (2003) Induction of chromosomal instability by chronic oxidative stress, Neoplasia. 5, 339-346.
Little J.B., Morgan W.F. (Eds.) (2003) Oncogene 13, 69-77.
Little, J.B., Azzam, E.I., De Toledo, S.M., Nagasawa, H. (2002) Bystander effects: intercellular transmission of radiation damage signals, Radiat. Prot. Dosim. 99, 159-162.
Lorimore, S.A, Wright, E.G. (2003) Radiation-induced genomic instability and bystander effects: related inflammatory-type responses to radiation-induced stress and injury? A review, Int. J. Radiat. Biol. 79, 15-25.
Lorimore, S.A., Coates, P.J., Scobie, G.E., Milne, G., Wright, E.G. (2001) Inflammatory-type responses after exposure to ionizing radiation in vivo: a mechanism for radiation-induced bystander effects?, Oncogene 20, 7085-7095.
Lorimore, S.A., Coates, P.J., Wright, E.G. (2003) Radiation-induced genomic instability and bystander effects: inter-related nontargeted effects of exposure to ionizing radiation, Oncogene 22, 7058-7069.
Lyng, F.M., Seymour, C.B., Mothersill, C. (2000) Production of a signal by irradiated cells which leads to a response in unirradiated cells characteristic of initiation of apoptosis, Br. J. Cancer. 83, 1223-1230.
Lyng, F.M., Seymour, C.B., Mothersill, C. (2002a) Early events in the apoptotic cascade initiated in cells treated with medium from the progeny of irradiated cells, Radiat. Prot. Dosim. 99, 169-172.
Lyng, F.M., Seymour, C.B., Mothersill, C. (2002b) Initiation of apoptosis in cells exposed to medium from the progeny of irradiated cells: a possible mechanism for bystander-induced genomic instability?, Radiat. Res. 157, 365-370.
Maguire M., Mothersill C., Seymour C.B., Lyng F.M. (2005) An adaptive response following exposure of cultures to medium from cells irradiated to low doses of cobalt 60 gamma rays, Radiat. Res. (in preparation).
Morgan, W.F. (2003) Non-targeted and delayed effects of exposure to ionizing radiation: I. Radiation-induced genomic instability and bystander effects in vitro, Rad. Res. 159, 567-580.
Mothersill, C., Seymour, C. (1997a) Medium from irradiated human epithelial cells but not human fibroblasts reduces the clonogenic survival of unirradiated cells, Int. J. Radiat. Biol. 71, 21-7.
Mothersill, C., Seymour, C. (1997b) Survival of human epithelial cells irradiated with cobalt 60 as microcolonies or single cells, Int. J. Radiat. Biol. 72, 597-606.
Mothersill, C., Seymour, C.B. (1998) Cell-cell contact during gamma irradiation is not required to induce a bystander effect in normal human keratinocytes: evidence for release during irradiation of a signal controlling survival into the medium, Radiat. Res. 149, 256-262.
Mothersill, C., Seymour, C.B. (2002) Bystander and delayed effects after fractionated radiation exposure, Radiat. Res. 158, 626-633.
Mothersill, C., Seymour, C. (2003) Low-dose radiation effects: experimental hematology and the changing paradigm, J. Exp. Haematol. 31, 437-445.
Mothersill, C., Lyng, F., O’reilly S., Harney J., Seymour C.B. (1996) Expression of lethal mutations is suppressed in neoplastically transformed cells and after treatment of normal cells with carcinogens, Radiat. Res. 145, 714-721.
Mothersill, C., Crean, M., Lyons, M., Mcsweeney, J., Mooney, R., O’reilly J., Seymour C.B. (1998) Expression of delayed toxicity and lethal mutations in the progeny of human cells surviving exposure to radiation and other environmental mutagens, Int. J. Radiat. Biol. 74, 673-680.
Mothersill, C., Stamato, T.D., Perez, M.L., Cummins, R., Mooney, R., Seymour, C.B. (2000) Involvement of energy metabolism in the production of ‘bystander effects’ by radiation, Br. J. Cancer. 82, 1740-1746.
Mothersill, C., Rea, D., Wright, E.G., Lorimore, S.A., Murphy, D., Seymour, C.B., O’malley K. (2001) Individual variation in the production of a ‘bystander signal’ following irradiation of primary cultures of normal human urothelium, Carcinogenesis 22, 1465-1471.
Mothersill, C., Seymour, C.B., Joiner, M.C. (2002) Relationship between radiation-induced low-dose hypersensitivity and the bystander effect, Radiat. Res. 157, 526-532.
Mothersill C., Seymour R.J., Seymour C.B. (2005) Bystander effects in repair deficient cell lines, Radiat. Res. (accepted).
Nagar, S., Smith, L.E., Morgan, W.F. (2003) Characterization of a novel epigenetic effect of ionizing radiation: the death-inducing effect, Cancer. Res. 63, 324-328.
Nagasawa, H., Little, J.B. (1992) Induction of sister chromatid exchanges by extremely low doses of alpha-particles, Cancer Res. 52, 6394-6396.
Nagasawa, H., Huo, L., Little, J.B. (2003) Increased bystander mutagenic effect in DNA double-strand break repair-deficient mammalian cells, Int. J. Radiat. Biol. 79, 35-41.
Osterreicher, J., Prise, K.M., Michael, B.D., Vogt, J., Butz, T., Tanner, J.M. (2003) Radiation-induced bystander effects. Mechanisms, biological implications, and current investigations at the Leipzig LIPSION facility, Strahlenther Onkol. 179, 69-77.
Prise, K.M., Belyakov, O.V., Folkard, M., Michael, B.D. (1998) Studies of bystander effects in human fibroblasts using a charged particle microbeam, Int. J. Radiat. Biol. 74, 793-798.
Prise, K.M., Belyakov, O.V., Newman, H.C., Patel, S., Schettino, G., Folkard, M., Michael, B.D. (2002) Non-targeted effects of radiation: bystander responses in cell and tissue models, Radiat. Prot. Dosim. 99, 223-226.
Prise, K.M., Folkard, M., Michael, B.D. (2003) A review of the bystander effect and its implications for low-dose exposure, Radiat. Prot. Dosim. 104, 347-355.
Reznikov, K., Kolesnikova, L., Pramanik, A., Tan-No, K., Gileva, I., Yakovleva, T., Rigler, R., Terenius, L., Bakalkin, G. (2000) Clustering of apoptotic cells via bystander killing by peroxides, FASEB J. 14, 1754-1764.
Sawant, S.G., Zheng, W., Hopkins, K.M., Randers-Pehrson, G., Lieberman, H.B., Hall, E.J. (2002) The radiation-induced bystander effect for clonogenic survival, Radiat. Res. 157, 361-364.
Seymour, C.B., Mothersill, C. (2000) Relative contribution of bystander and targeted cell killing to the low-dose region of the radiation dose-response curve, Radiat. Res. 153, 508-511.
Seymour, C.B., Mothersill, C., Mooney, R., Moriarty, M., Tipton, K.F. (2003) Monoamine oxidase inhibitors l-deprenyl and clorgyline protect nonmalignant human cells from ionising radiation and chemotherapy toxicity, Br. J. Cancer. 89, 1979-1986.
Shao, C., Furusawa, Y., Kobayashi, Y., Funayama, T., Wada, S. (2003) Bystander effect induced by counted high-LET particles in confluent human fibroblasts: a mechanistic study, FASEB J. 17, 1422-1427.
Trosko J.E. (1998) Hierarchical and cybernetic nature of biologic systems and their relevance to homeostatic adaptation to low-level exposures to oxidative stress-inducing agents, Environ. Health Perspect. 106 (Suppl. 1), 331-339.
Zhou, H., Randers-Pehrson, G., Suzuki, M., Waldren, C.A., Hei, T.K. (2002) Genotoxic damage in non-irradiated cells: contribution from the bystander effect, Radiat. Prot. Dosim. 99, 227-232.
Zhou, H., Randers-Pehrson, G., Geard, C.R., Brenner, D.J., Hall, E.J., Hei, T.K. (2003) Interaction between radiation-induced adaptive response and bystander mutagenesis in mammalian cells, Radiat. Res. 160, 512-516.