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Microscopic behaviour of DNA during electrophoresis: electrophoretic orientation

  • Bengt Nordén (a1), Christer Elvingson (a1), Mats Jonsson (a1) and Björn Åkerman (a1)

Extract

The study of the behaviour of DNA when subjected to electric fields poses several intriguing problems of fundamental physico-chemical importance. Electric field (Kerr effect) orientation of DNA in free solution as well as migration of DNA in gel electrophoresis are two well-established, but so far rather separate, research fields. Whereas the first one has been generally concerned with basic structural and dynamical properties of DNA (Charney, 1988), the second is closely related to techniques of molecular biology (for a review on DNA electrophoresis, see stellwagen 1987).

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