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The revolution of personalized psychiatry: will technology make it happen sooner?

  • G. Perna (a1) (a2) (a3), M. Grassi (a1), D. Caldirola (a1) and C. B. Nemeroff (a3)


Personalized medicine (PM) aims to establish a new approach in clinical decision-making, based upon a patient's individual profile in order to tailor treatment to each patient's characteristics. Although this has become a focus of the discussion also in the psychiatric field, with evidence of its high potential coming from several proof-of-concept studies, nearly no tools have been developed by now that are ready to be applied in clinical practice. In this paper, we discuss recent technological advances that can make a shift toward a clinical application of the PM paradigm. We focus specifically on those technologies that allow both the collection of massive as much as real-time data, i.e., electronic medical records and smart wearable devices, and to achieve relevant predictions using these data, i.e. the application of machine learning techniques.

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Corresponding author

*Address for correspondence: G. Perna, Department of Clinical Neurosciences, Villa San Benedetto Menni, Hermanas Hospitalarias, FoRiPsi, via Roma 16, 22032 Albese con Cassano, Como, Italy. (Email:


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The revolution of personalized psychiatry: will technology make it happen sooner?

  • G. Perna (a1) (a2) (a3), M. Grassi (a1), D. Caldirola (a1) and C. B. Nemeroff (a3)


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