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This issue features papers using functional imaging in psychiatric disorders linked with neuropsychology to explore underlying brain systems, together with other neuropsychological papers, and a related Invited Review by Nelson et al. (pp. 163–174) on neural changes which may underlie the developmental social changes of adolescence. Three papers deal with psychiatric disorders in childhood and adolescence. Two further papers report studies of suicidal behaviours and of depression. An additional paper from Barrett et al. (pp. 281–293) describes the prevalence and features of schizophrenia in an unusual cultural population isolate, the Iban of Sarawak.