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The growth hormone response to insulin induced hypoglycaemia in alcoholics

  • R. J. Chalmers (a1), E. H. Bennie (a1), R. H. Johnson (a1) and H. G. Kinnell (a1)

Synopsis

The growth hormone response to insulin induced hypoglycaemia was studied in 7 alcoholic in-patients who had been abstinent for 2–11 days and in 10 normal controls. Blood samples were taken at intervals after the injection of soluble insulin (0·1 U/kg body weight). The growth hormone response was impaired in 4 of the alcoholics and the depression was not related to differences in blood glucose or plasma free fatty acids. The Cortisol response was also impaired in the alcoholics. We conclude that alcoholics observed after alcohol withdrawal may have a depression of hypothalamic/pituitary function.

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Corresponding author

1Address for correspondence: Dr R. J. Chalmers, The University Department of Neurology, Institute of Neurological Sciences, Southern General Hospital, Glasgow G51 4TF.

References

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The growth hormone response to insulin induced hypoglycaemia in alcoholics

  • R. J. Chalmers (a1), E. H. Bennie (a1), R. H. Johnson (a1) and H. G. Kinnell (a1)

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