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Electrodermal activity in the affective disorders and schizophrenia

Published online by Cambridge University Press:  09 July 2009

B. K. Toone ,
E. Cooke  and
M. H. Lader
B. K. Toone*
Affiliation:
Institute of Psychiatry, London
E. Cooke
Affiliation:
Institute of Psychiatry, London
M. H. Lader
Affiliation:
Institute of Psychiatry, London
*
1Address for correspondence: Dr B. K. Toone, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London SE5 8AF.
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Synopsis

Electrodermal activity was measured bilaterally at rest and during stimulation in 22 schizophrenic, 11 depressed and 12 anxiety state patients, and in 32 normal volunteers. No group showed a distinctive pattern of lateral asymmetry. The frequency of spontaneous fluctuations in electrodermal activity was greater in the anxiety state and schizophrenic groups and in those patients who reported auditory hallucinations during recording. Few schizophrenic subjects failed to respond to visual stimulation but a substantial minority failed to habituate. The implications of these findings are discussed.

Type
Research Article
Information
Psychological Medicine , Volume 11 , Issue 3 , August 1981 , pp. 497 - 508
Copyright
Copyright © Cambridge University Press 1981

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References

Alpert, M., Rubinstein, H. & Kesselman, M. (1976). Asymmetry of information processing in hallucinators and non hallucinators. Journal of Nervous and Mental Disease 162 (6), 258–265.Google Scholar
Annett, M. (1970). A classification of hand preferences by association analysis. British Journal of Psychology 61, 303–321.Google Scholar
Ax, A. F., Bamford, J. L., Beckett, P. G. S., Frets, N. F. & Gottlieb, J. S. (1970). Autonomic conditioning in chronic schizophrenia. Journal of Abnormal Psychology 76 (1), 140–154.CrossRefGoogle ScholarPubMed
Bagg, C. E. & Crookes, T. G. (1966). Palmar digital sweating in women suffering from depression. British Journal of Psychiatry 112, 1251–1255.CrossRefGoogle ScholarPubMed
Beard, A. W. (1963). The schizophrenic-like psychoses of epilepsy: II. Physical aspects. British Journal of psychiatry 109, 113–129.Google Scholar
Bernstein, A. S. (1964). The galvanic skin response orienting reflex among chronic schizophrenics. Psychonomic Science 1, 391–392.CrossRefGoogle Scholar
Bernstein, A. S. (1967). Electrodermal base level, tonic arousal, and adaptation in chronic schizophrenics. Journal of Abnormal Psychology 72, 221–232.CrossRefGoogle ScholarPubMed
Bernstein, A. S. (1970). Phasic electrodermal orienting response in chronic schizophrenics: II. Response to auditory signals of varying intensity. Journal of Abnormal Psychology 75 (2), 146.–156.CrossRefGoogle ScholarPubMed
Bond, A. & Lader, M. H. (1974). The use of analogue scales in rating subjective feelings. British Journal of Medical Psychology 47, 211–218.CrossRefGoogle Scholar
Burdick, J. A. (1968). Arousal measurement in schizophrenics and normals. Activitas Nervosa Superior 10, 369–372.Google Scholar
Carmon, A. & Nachshon, I. (1973). Ear asymmetry in perception of emotional non-verbal stimuli. Acta Psychologica 37, 351–357.CrossRefGoogle ScholarPubMed
Davison, K. & Bagley, C. R. (1969). Schizophrenia-like psychoses associated with organic disorders of the central nervous system: a review of the literature. In Current Problems in Neuropsychiatry (ed. Herrington, R. N.), pp. 113–184. British Journal of Psychiatry Special Publication No.4. Headley Brothers: Ashford, Kent.Google Scholar
Deakin, J. F. W., Baker, H. F., Frith, C. D., Joseph, M. H. & Johnstone, E. C. (1979). Arousal related to excretion of noradrenaline metabolites and clinical aspects of unmedicated chronic schizophrenic patients. Journal of Psychiatric Research 15, 57–65.Google Scholar
Dimond, S. J., Farrington, L. & Johnson, P. (1976). Differing emotional response from right and left hemispheres. Nature 261, 690–692.Google Scholar
Flor-Henry, P. (1969). Psychosis and temporal lobe epilepsy: a controlled investigation. Epilepsia 10, 363–395.CrossRefGoogle ScholarPubMed
Frith, C. D., Stevens, M., Johnstone, E. C. & Crow, T. J. (1979). Skin conductance responsivity during acute episodes of schizophrenia as a predictor of symptomatic improvement. Psychological Medicine 9, 101–106.Google Scholar
Galin, D. (1974). Implications for psychiatry of left and right cerebral specialization. Archives of General Psychiatry 31, 572–583.CrossRefGoogle ScholarPubMed
Gibson, A. C. (1978). Depot injections and tardivedyskinesia. British Journal of Psychiatry 133, 361–365.CrossRefGoogle Scholar
Goldstein, I. B. (1965). Relationship of muscle tension and autonomic activity to psychiatric disorders. Psychosomatic Medicine, 27, 39–52.Google Scholar
Goldstein, M. J. & Acker, C. W. (1967). Psychophysiological reactions to films by chronic schizophrenics: II. Individual differences in resting levels and reactivity. Journal of Abnormal Psychology 72(1), 23–29.CrossRefGoogle Scholar
Gruzelier, J. H. (1973). Bilateral asymmetry of skin conductance orienting activity and levels in schizophrenia. Biological Psychology 1, 21–41.CrossRefGoogle Scholar
Gruzelier, J. H. (1976). Clinical attributes of schizophrenic skin conductance responders and non-responders. Psychological Medicine 6, 245–249.Google Scholar
Gruzelier, J. H. & Hammond, N. V. (1978). The effect of chlorpromazine upon psychophysiological, endocrine and information processing measures in schizophrenia. Journal of Psychiatric Research 14, 167–182.CrossRefGoogle ScholarPubMed
Gruzelier, J. H. & Venables, P. H. (1972). Skin conductance orienting activity in a heterogenous sample of schizophrenics: possible evidence of limbic dysfunction. Journal of Nervous and Mental Disease 155, 277–287.CrossRefGoogle Scholar
Gruzelier, J. H. & Venables, P. H. (1974). Bimodality and lateral asymmetry of skin conductance orienting activity in schizophrenics: replication and evidence of lateral asymmetry in patients with depression and disorders of personality. Biological Psychiatry 8, 55–73.Google Scholar
Gur, R. (1977). Motoric laterality imbalance in schizophrenia. Archives of General Psychiatry 34, 33–37.Google Scholar
Gur, R. (1978). Left hemisphere dysfunction and left hemisphere overactivation in schizophrenia. Journal of Abnormal Psychology 87 (2), 226–238.Google Scholar
Haggard, M. P. & Parkinson, A. M. (1971). Stimulus and task factors as determinants of ear advantages. Quarterly Journal of Experimental Psychology 23, 168–177.Google Scholar
Hammond, N. V. & Gruzelier, J. H. (1978). Laterality attention and rate effects in the auditory temporal discrimination of chronic schizophrenics: the effect of treatment with chlorpromazine. Quarterly Journal of Experimental Psychology 30, 91–103.CrossRefGoogle ScholarPubMed
Hecaen, H. & Ajuriaguerra, J. de (1964). Left Handedness. Grune and Stratton: New York.Google Scholar
Howe, E. (1958). SCR conditioning in anxiety states, normals and chronic functioning schizophrenic subjects. Journal of Abnormal and Social Psychology 56, 183–189.Google Scholar
Johnstone, E. C., Crow, T. J., Frith, C. D., Husband, J. & Kreel, L. (1976). Cerebral ventricular size and cognitive impairment in chronic schizophrenia. Lancet ii, 924–926.Google Scholar
Joyce, C. R. B. (1968). Psychopharmacology: Dimensions and Perspectives. Tavistock Publications: London.Google Scholar
Kristensen, O. & Sindrup, E. H. (1978). Psychomotor epilepsy and psychosis: II. Electroencephalographic findings. Acta neurologica scandinavica 57, 370–379.Google Scholar
Kugler, B. T. & Gruzelier, J. H. (1979). The influence of chlorpromazine and amylobarbitone on the recovery limb of the electrodermal response. Psychiatry Research 2, 75–84.CrossRefGoogle Scholar
Lader, M. H. & Wing, L. (1966). Physiological Measures, Sedative Drugs, and Morbid Anxiety. Maudsley Monograph No. 14. Oxford University Press: London.Google Scholar
Lishman, W. A. & McMeekan, E. R. L. (1976). Hand preference patterns in psychiatric patients. British Journal of Psychiatry 129, 158–166.Google Scholar
Little, J. C., Kerr, T. A. & McLelland, H. A. (1978). Where are the untreated depressions?. British Medical Journal i, 1593–1594.CrossRefGoogle Scholar
Lorr, M. (1953). Multidimensional scale for rating psychiatric patients. United States Veterans Administrative and Technical Bulletin TB 10–507, 1–44.Google Scholar
Magaro, P. A. (1973). Skin conductance basal level and reactivity in schizophrenia as a function of chronicity, premorbid adjustment, diagnosis and medication. Journal of Abnormal Psychology 81, (3), 270–281.CrossRefGoogle ScholarPubMed
Maricq, H. R. & Weinrich, M. C. (1980). Psychophysiological studies in schizophrenic patients selected on the basis of a ‘genetic marker’. Acta psychiatrica scandinavica 61, 185–208.Google Scholar
Noble, P. J. & Lader, M. H. (1971). Salivary secretion and depressive illness: a physiological and psychometric study. Psychological Medicine 2, 372–376.Google Scholar
Patterson, T. (1976). Skin conductance responding/non- responding and pupillometrics in chronic schizophreni. Journal of Nervous and Mental Disease 163 (3), 200–209.CrossRefGoogle Scholar
Pishkin, V. & Hershiser, D. (1963). Respiration and GSR as functions of white sound in schizophrenia. Journal of Consulting Psychology 27 (4), 330–337.Google Scholar
Porter, J. M. (1938). Adaptation of the galvanic skin response. Journal of Experimental Psychology 23, 553–557.CrossRefGoogle Scholar
Raskin, M. (1975). Decreased skin conductance response habituation in chronically anxious patients. Biological Psychology 2, 309–319.Google Scholar
Rossi, S. F. & Rosadini, G. (1967). Experimental analysis of cerebral dominance in man. In Brain Mechanisms Underlying Speech and Language (ed. Millikan, D. H. and Darley, F. L.), pp. 167–184. Grune and Stratton: New York.Google Scholar
Serafetinides, E. A. (1972). Laterality and voltage in the EEG of psychiatric patients. Diseases of the Nervous System 33, 622–623.Google ScholarPubMed
Serafetinides, E. A. (1973). Voltage laterality in the EEG of psychiatric patients. Diseases of the Nervous System 34, 190–191.Google Scholar
Slade, P. D. (1975). An experimental approach to the study of auditory hallucinations. Ph.D. thesis: University of London.Google Scholar
Spohn, H. E., Thetford, P. E. & Cancro, R. (1971). The effects of phenothiazine medication on skin conductance and heart rate in schizophrenic patients. Journal of Nervous and Mental Disease 152, (2), 129–139.Google Scholar
Stern, J. A., Surphlis, W. & Koff, E. (1965). Electrodermal responsiveness as related to psychiatric diagnosis and prognosis. Psychophysiology 2 (1), 51–61.Google Scholar
Storey, P. B. (1966). Lumbar air encephalography in schizophrenia: a controlled experiment. British Journal of Psychiatry 112, 135–144.Google Scholar
Suberi, M. & McKeever, W. F. (1977). Differential right hemisphere memory storage of emotional and non-emotional faces. Neuropsychologia 15, 757–768.CrossRefGoogle ScholarPubMed
Tan, B. K. (1964). Physiological correlates of anxiety. Canadian Psychiatric Association Journal 9, 63–71.Google Scholar
Tarrier, N., Vaughn, C., Lader, M. H. & Leff, J. (1979). Bodily reactions to people and events in schizophrenics. Archives of General Psychiatry 36, 311–315.Google Scholar
Tecce, J. J. & Cole, J. O. (1972). Psychophysiological responses of schizophrenics to drugs. Psychopharmacologia (Berlin) 24, 159–200.Google Scholar
Terzian, H. (1964). Behavioural and EEG effects of intracarotid sodium amytal injection. Acta neurochirurgia 12, 230–239.Google Scholar
Thayer, J. & Silber, D. E. (1971). Relationship between levels of arousal and responsiveness among schizophrenic and normal subjects. Journal of Abnormal Psychology 77, (2), 162–173.CrossRefGoogle ScholarPubMed
Toone, B. K. & Driver, M. (1981). In preparation.Google Scholar
Toone, B. K. & Lader, M. H. (1979). Salivary secretion in the affective disorders and schizophrenia. Acta psychiatrica scandinavica 59, 529–535Google Scholar
Toone, B. K., Cooke, E. & Lader, M. H. (1979). The effect of temporal lobe surgery on electrodermal activity: implications for an organic hypothesis in the aetiology of schizophrenia. Psychological Medicine 9, 281–285.CrossRefGoogle ScholarPubMed
Venables, P. H. (1973). The relationship between level of skin potential and fusion of paired light flashes in schizophrenic and normal subjects. Journal of Psychiatric Research 1, 279–287.CrossRefGoogle Scholar
Wing, J. K., Cooper, J. E. & Sartorius, N. (1974). The Measurement and Classification of Psychiatric Symptoms. Cambridge University Press: London.Google Scholar
Zahn, T. P. (1976). On the bimodality of the distribution of electrodermal orienting responses in schizophrenic patients. Journal of Nervous and Mental Disease 162, (3), 195–199.CrossRefGoogle ScholarPubMed
Zahn, T. P., Rosenthal, D. & Lawlor, W. G. (1968). Eletrodermal and heart rate orienting in chronic schizophrenia. Journal of Psychiatric Research 6, 117–134.CrossRefGoogle Scholar
Zuckerman, M., Persky, H. & Curtis, G. C. (1968). Relationships among anxiety, depression, hostility and autonomic variables. Journal of Nervous and Mental Disease 146, (6), 481–487.Google Scholar