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Drug response patterns as a basis of nosology for the mood-incongruent psychoses (the schizophrenias)

Published online by Cambridge University Press:  09 July 2009

David L. Garver ,
Kathleen Kelly ,
Karen A. Fried ,
Mary Magnusson  and
Jack Hirschowitz
David L. Garver*
Affiliation:
Department of Psychiatry and Department of Pharmacology and Cell Biophysics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
Kathleen Kelly
Affiliation:
Department of Psychiatry and Department of Pharmacology and Cell Biophysics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
Karen A. Fried
Affiliation:
Department of Psychiatry and Department of Pharmacology and Cell Biophysics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
Mary Magnusson
Affiliation:
Department of Psychiatry and Department of Pharmacology and Cell Biophysics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
Jack Hirschowitz
Affiliation:
Department of Psychiatry and Department of Pharmacology and Cell Biophysics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA
*
1 Address for correspondence: Dr David L. Garver, Department of Psychiatry, University of Cincinnati College of Medicine, 231 Bethesda Avenue, Cincinnati, OH 45267–0559, USA.
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Synopsis

Interaction of therapeutic drugs with a series of different biopathological substrates of psychosis might be expected to generate a series of different response patterns. Herein the authors suggest that multi-modal response patterns following lithium and neuroleptic treatment of psychotic patients may aid in resolving the heterogeneity of psychotic disorders and lead to a new nosology of the psychoses.

Type
Research Article
Information
Psychological Medicine , Volume 18 , Issue 4 , November 1988 , pp. 873 - 885
Copyright
Copyright © Cambridge University Press 1988

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