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Disappearance of chlorpromazine from plasma following drug withdrawal

  • Oliver Phillipson (a1), Janet Baker (a1), Frank Sebastianpillai (a1), Graham Sheppard (a1) and Peter Brook (a1)...

Synopsis

Plasma chlorpromazine measured by a gas chromatographic procedure was found to disappear rapidly during the first week after withdrawal of chlorpromazine treatment in a group of 17 chronically hospitalized patients. The drug or its metabolites were no longer measurable in plasma after 8 days.

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Corresponding author

3Address for correspondence: Dr Graham Sheppard, MRC Neurochemical Pharmacology Unit, Department of Pharmacology, Medical School, Hills Rd, Cambridge.

References

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Disappearance of chlorpromazine from plasma following drug withdrawal

  • Oliver Phillipson (a1), Janet Baker (a1), Frank Sebastianpillai (a1), Graham Sheppard (a1) and Peter Brook (a1)...

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