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Decision making in euthymic bipolar I and bipolar II disorders

Published online by Cambridge University Press:  22 September 2010

D. J. Martino ,
S. A. Strejilevich ,
T. Torralva  and
F. Manes
D. J. Martino
Affiliation:
Institute of Neurosciences, Favaloro University, Buenos Aires, Argentina
S. A. Strejilevich*
Affiliation:
Institute of Neurosciences, Favaloro University, Buenos Aires, Argentina Institute of Cognitive Neurology (INECO), Buenos Aires, Argentina
T. Torralva
Affiliation:
Institute of Neurosciences, Favaloro University, Buenos Aires, Argentina Institute of Cognitive Neurology (INECO), Buenos Aires, Argentina
F. Manes
Affiliation:
Institute of Neurosciences, Favaloro University, Buenos Aires, Argentina Institute of Cognitive Neurology (INECO), Buenos Aires, Argentina
*
*Address for correspondence: Dr S. A. Strejilevich, Congreso 2477 Dto. D, 1428 Ciudad de Buenos Aires, Argentina. (Email: sstrejilevich@ffavaloro.org)
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Abstract

Background

The main aim of this study was to compare a large population of patients with bipolar disorder (BD) types I and II strictly defined as euthymic with healthy controls on measures of decision making. An additional aim was to compare performance on a decision-making task between patients with and without a history of suicide attempt.

Method

Eighty-five euthymic patients with BD-I or BD-II and 34 healthy controls were included. All subjects completed tests to assess verbal memory, attention and executive functions, and a decision-making paradigm (the Iowa Gambling Task, IGT).

Results

Both groups of patients had worse performance than healthy controls on measures of verbal memory, attention and executive function. No significant differences were found between BD-I, BD-II and healthy controls on measures of decision making. By contrast, patients with a history of suicide attempt had lower performance in the IGT than patients without a history of suicide attempt.

Conclusions

Patients with euthymic BD-I and BD-II had intact decision-making abilities, suggesting that this does not represent a reliable trait marker of the disorder. In addition, our results provide further evidence of an association between impairments in decision making and vulnerability to suicidal behavior.

Keywords

Bipolar I and II disorderdecision makingeuthymiaIowa Gambling Task
Type
Original Articles
Information
Psychological Medicine , Volume 41 , Issue 6 , June 2011 , pp. 1319 - 1327
Copyright
Copyright © Cambridge University Press 2010

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