Hostname: page-component-76fb5796d-9pm4c Total loading time: 0 Render date: 2024-04-25T14:27:55.244Z Has data issue: false hasContentIssue false
  • English
  • Français

An unusual presentation of multiple sclerosis

Published online by Cambridge University Press:  09 July 2009

M. H. Hotopf ,
S. Pollock  and
W. A. Lishman
M. H. Hotopf
Affiliation:
Maudsley Hospital, Brook Hospital and Institute of Psychiatry, London
S. Pollock
Affiliation:
Maudsley Hospital, Brook Hospital and Institute of Psychiatry, London
W. A. Lishman*
Affiliation:
Maudsley Hospital, Brook Hospital and Institute of Psychiatry, London
*
1 Address for correspondence: Professor W. A. Lishman, Institute of Psychiatry, De Crespigny Park, London SE5 8AF
Get access Rights & Permissions [Opens in a new window]

Synopsis

Two male patients who presented with unusual pictures of dementia in the absence of other obvious symptoms or signs are reported. Investigations demonstrated changes highly suggestive of multiple sclerosis (MS) on magnetic resonance imaging, cerebrospinal fluid analysis and electrophysiological tests. We suggest this represents a rare presentation of multiple sclerosis.

Type
Case Report
Information
Psychological Medicine , Volume 24 , Issue 2 , May 1994 , pp. 525 - 529
Copyright
Copyright © Cambridge University Press 1994

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Filley, C. M., Heaton, R. K., Nelson, L. M., Burks, J. S. & Franklin, T. G. (1989). A comparison of dementia in Alzheimer's disease and multiple sclerosis. Archives of Neurology 46, 157–161.CrossRefGoogle ScholarPubMed
Franklin, G. M., Nelson, L. M., Filley, C. M. & Heaton, R. K., (1989). Cognitive loss in multiple sclerosis: case reports and a review of the literature. Archives of Neurology 46, 162–167.CrossRefGoogle Scholar
Heaton, R. K., Nelson, L. M., Thompson, D. S., Burk, J. S. & Franklin, G. M. (1985). Neuropsychological findings in relapsing remitting and chronic-progressive multiple sclerosis. Journal of Consulting and Clinical Psychology 53, 103–110.CrossRefGoogle ScholarPubMed
Koenig, H. (1968). Dementia associated with the benign form of multiple sclerosis. Transactions of the American Neurological Association 93, 227–231.Google Scholar
Lishman, W. A. (1987). Organic Psychiatry, 2nd edn. Blackwell Scientific Publications: Oxford.Google Scholar
Logsdail, K. L., Callanan, M. M. & Ron, M. A. (1988). Psychiatric morbidity in patients with clinically isolated lesions of the type seen in multiple sclerosis: a clinical and MRI study. Psychological Medicine 18, 355–364.Google Scholar
Rao, S. M., Leo, G. J.Haughton, V. M., St. Aubin-Faubert, P. & Bernardin, L. (1989). Correlation of magnetic resonance imaging with neuropsychological testing in multiple sclerosis. Neurology 39, 161–166.Google Scholar
Rao, S. M., Leo, G. L., Bernardin, L. & Unverzagt, M. S. (1991). Cognitive dysfunction in multiple sclerosis. I. Frequency, patterns and prediction. Neurology 41, 685–691.Google Scholar
Ron, M. A. (1986). Multiple sclerosis: psychiatric and psychometric abnormalities. Journal of Psychosomatic Research 30, 2–11.Google Scholar
Skegg, K., Corwin, P. A. & Skegg, D. C. G. (1988). How often is multiple sclerosis mistaken for a psychiatric disorder? Psychological Medicine 18, 733–736.CrossRefGoogle ScholarPubMed
Surridge, D. (1969). An investigation into some psychiatric aspects of multiple sclerosis. British Journal of Psychiatry 115, 749–764.CrossRefGoogle ScholarPubMed