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Dietary and metabolic effects on rhesus social behaviour: neonatal thyroxine reductions

Published online by Cambridge University Press:  09 July 2009

Arnold. S. Chamove*
Affiliation:
From the Department of Psychology, University of Stirling, Stirling
*
1Address for correspondence: Dr A. S. Chamove, Department of Psychology, University of Stirling, Stirling, Scotland FK9 4LA.

Synopsis

Assessment was made of the behavioural development of 3 monkeys whose levels of thyroxine were reduced by being given 131I and another 3 monkeys given a thyroxine depressant (TCAP) during the first weeks of life and maintained with low thyroxine levels for 3 months. When subsequently tested at normal thyroxine levels, these experimental subjects showed less positive social behaviour when compared with controls. When confronted with unfamiliar monkeys, the two experimental groups were less fearful than controls and also showed a lack of differential responsiveness in varying social situations, suggesting a low level of emotion. A foetal athyreotic group is also described.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1984

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References

REFERENCES

Allen, J. R., Lalich, J. J. & Schmidt, U. J. (1965). Effects of 1, 1, 3-trycyano-2-amino-1-propene on the thyroid of the rat. Laboratory Investigation 14, 14121418.Google ScholarPubMed
Balzas, R. (1975). Postnatal development of the rat brain: effects of thyroid state. In Brain Development and Thyroid Deficiency (ed. Querido, A. and Swaab, D. F.), pp. 2236. North-Holland: New York.Google Scholar
Chamove, A. S. (1978). Therapy of isolate rhesus: different partners and social behavior. Child Development 49, 4350.CrossRefGoogle ScholarPubMed
Chamove, A. S. (1980). Dietary and metabolic effects on rhesus social behaviour: protein and protein–calorie undernutrition. Developmental Psychobiology 13, 287298.CrossRefGoogle Scholar
Chamove, A. S., Eysenck, H. J. & Harlow, H. F. (1972). Personality in monkeys: factor analyses of rhesus social behaviour. Quarterly Journal of Experimental Psychology 24, 496504.CrossRefGoogle ScholarPubMed
Davenport, J. W. (1970). Cretinism in rats: enduring behavioral deficit induced by tricyanoaminopropene. Science 167, 10071009.CrossRefGoogle ScholarPubMed
Davenport, J. W. (1976). Environmental therapy in hypothyroid and other disadvantaged animal populations. In Environments as Therapy for Brain Dysfunction (ed. Walsh, R. N. and Greenough, W. T.), pp. 171200. Plenum: New York.Google Scholar
Davenport, J. W. & Hennies, R. S. (1967). Perinatal hypothyroidism in rats: persistent motivational and metabolic effects. Developmental Psychobiology 9, 6782.CrossRefGoogle Scholar
Davenport, J. W., Kerr, G. R. & Scheffler, G. (1971). Behavioral development of thyroidectomized monkeys. Mainly Monkeys 2, 46.Google Scholar
Davenport, J. W., Hagquist, W. W. & Hennies, R. S. (1975). Neonatal hyperthyroidism, maturational acceleration and learning deficit in triiodothyronine-stimulated rats. Physiological Psychology 3, 231236.CrossRefGoogle Scholar
Korn, J. H. (1967). Conditioned activity depression in hypothyroid and hyperthyroid rats. Journal of Genetic Psychology 110, 169180.CrossRefGoogle ScholarPubMed
Means, J., De Groot, L. & Stanbury, J. (1963). The Thyroid and Its Diseases. McGraw-Hill: London.Google Scholar
Passingham, R. (1982). The Human Primate. W. H. Freeman: San Francisco.Google Scholar
Pickering, D. E., Smyth, F. S., Van Wagenen, G. & Fisher, D. A. (1953). Growth and metabolism in normal and thyroid-ablated infant rhesus monkeys. American Journal of Diseases of the Child 86, 1161.Google ScholarPubMed
Robertson, E. E. (1978). Organic disorders. In Companion to Psychiatric Studies (ed. Forrest, A., Affleck, J. A. and Zeallery, J.), pp. 458491. Churchill Livingstone: Edinburgh.Google Scholar
Schalock, R. L., Brown, W. J. & Smith, R. L. (1977). Neonatal hypothyroidism: behavioural, thyroid hormonal and neuroanatomical effects. Physiology and Behavior 19, 489491.CrossRefGoogle ScholarPubMed
Schapiro, S. & Norman, R. J. (1967). Thyroxine: effects of neonatal administration on maturation, development, and behavior. Science 155, 12791281.CrossRefGoogle ScholarPubMed
Sjoden, P. O. & Lindqvist, L. (1978). Behavioural effects of neonatal thyroid hormones and differential postweaning rearing in rats. Developmental Psychobiology 11, 371383.CrossRefGoogle ScholarPubMed
Sobrian, S. K., Pappas, B. A., Edson, N., Rastogi, R. & Singhal, R. L. (1976). Alterations in behavioural ontogeny following neonatal radiothyroidectomy in the rat. Research Communications in Psychology, Psychiatry and Behaviour 1, 419434.Google Scholar
Whatson, T. S., Smart, J. L. & Dobbing, J. (1976). Undernutrition in early life: lasting effects on activity and social behavior of male and female rats. Developmental Psychobiology 9, 529538.CrossRefGoogle ScholarPubMed
Whybrow, P. & Ferrel, R. (1974). Thyroid states in human behavior. In The Thyroid Axis, Drugs, and Behavior (ed. Prange, A. J.), pp. 525. Raven Press: New York.Google Scholar