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Organ fuel selection: brain

Published online by Cambridge University Press:  28 February 2007

Stephanie A. Amiel
Affiliation:
UMDS, Guy' Hospital, London SEl 9RT
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Abstract

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Type
Meeting Report
Copyright
Copyright © The Nutrition Society 1995

References

Amiel, S. A. (1994). Hypoglycaemia without warning: a dangerous but reversible phenomenon. The Endocrinologist 4, 433441.Google Scholar
Amiel, S. A., Archibald, H. R., Chusney, G. & Gale, E. A. M. (1991 a). Ketone lowers hormone responses to hypoglycaernia – evidence for acute cerebral utilization of a non-glucose fuel. Clinical Science 81, 189194.CrossRefGoogle ScholarPubMed
Amiel, S. A., Pottinger, R. C., Archibald, H. R., Chusney, G., Cunnah, D. T. F., Prior, P. F. & Gale, E. A. M. (1991 b). Effect of antecedent glucose control on cerebral function during hypoglycemia. Diabetes Care 14, 109118.CrossRefGoogle ScholarPubMed
Amiel, S. A., Sherwin, R. S., Simonson, D. C. & Tamborlane, W. V. (1988). Effect of intensive insulin therapy on glycemic thresholds for counterregulatory hormone release. Diabefes 37, 901907.Google Scholar
Avogaro, A., Nosadini, R., Doria, A., Tremolada, C., Baccaglini, U., Ambrosio, F., Merkel, C., Nosadini, A., Trevisan, R. & Fioretto, P. (1990). Substrate availability other than glucose in the brain during euglycemia and insulin-induced hypoglycemia in dogs. Metabolism 39, 4650.CrossRefGoogle ScholarPubMed
Biggers, D. W., Myers, S. R., Neal, D., Stinson, R., Cooper, N. B., Jaspan, J. B., Williams, P. E., Cherrington, A. D. & Frizzell, R. T. (1989). Role of the brain in counterregulation of insulin induced hypoglycemia in dogs. Diabetes 38, 716.CrossRefGoogle ScholarPubMed
Crandall, E. A. & Fernstrom, J. D. (1983). Effect of experimental diabetes on the levels of aromatic and branched chain aminoacids in rat blood and brain. Diabetes 32, 222230.CrossRefGoogle ScholarPubMed
Cranston, I. A., Lomas, J., Maran, A., Macdonald, I. A. & Amiel, S. A. (1994). Restoration of hypoglycaemia awareness in patients with a long history of hypoglycaemia without warning. Lancet 344, 283287.CrossRefGoogle Scholar
Drenick, E. J., Alvarez, L. C., Tamasi, G. C. & Brickman, A. S. (1972). Resistance to symptomatic insulin reactions after fasting. Journal of Clinical Science 51, 27572762.Google ScholarPubMed
Fanelli, C., Di Vincenzo, A., Modarelli, F., Lepore, M., Ciofetta, M., Epifano, L., Pampanelli, S. Brunetti, P. & Bolli, G. B. (1993). Post-hypoglycaemic hyperketonaemia does not contribute to brain metabolism during insulin-induced hypoglycaemia in humans. Diabetologia 36, 11911197.CrossRefGoogle Scholar
Fourest-Fontecave, S., Adamson, U., Lins, P. E., Ekblomb, B., Sandahl, C. & Strand, L. (1987). Mental alertness in response to hypoglycaemia in normal man: the effect of 12 hours and 72 hours fasting. Diabéte et Métabolisme 13, 405410.Google Scholar
Hawkins, R. A., Williamson, D. H. & Krebs, H. A. (1971). Ketone body utilization by adult and suckling rat brain in vivo. Biochemical Journal 122, 1318.CrossRefGoogle ScholarPubMed
McCall, A. L., Fixman, L. B., Fleming, N., Tornheim, K., Chick, W. & Ruderman, N. (1986). Chronic hypoglycemia increases brain glucose transport. American Journal of Physiology 251, E442E447.Google ScholarPubMed
Maran, A., Cranston, I., Lomas, J., Macdonald, I. & Amiel, S. A. (1994). Protection of lactate of cerebral function during hypoglycaemia. Lancet 343, 1620.Google Scholar
Maran, A., Lomas, J., Macdonald, I. & Amiel, S. A. (1993). Lack of protection of cerebral function in well controlled diabetic patients with hypoglycemia unawareness. Diabetes 42 Suppl. 1., 46.Google Scholar
Mooradian, M. D. & Morin, A. M. (1991). Brain uptake of glucose in diabetes mellitus: the role of glucose transporters. American Journal of Medical Science 301, 173177.CrossRefGoogle ScholarPubMed
Nagy, R. J., O'Connor, A. & Boyle, P. J. (1992). Modest hypoglycemia impairs brain glucose utilization before onset of symptoms. Diabetes 41 Suppl. 1, 69A.Google Scholar
Nagy, R., O'Connor, A., Robinson, B. & Boyle, P. J. (1993). Hypoglycemia unawareness results from adaptation of brain glucose metabolism. Diabetes 42 Suppl. 1, 133A.Google Scholar
Owen, O. E., Morgan, A. P., Kemp, H. G., Sullivan, J. M., Herrara, H. G. & Cahill, G. F. (1967). Brain metabolism during fasting. Journal of Clinical Investigation 46, 15891595.Google Scholar
Pardridge, W. M., Triguero, D. & Farrell, C. R. (1990). Downregulation of blood–brain barrier glucose transporter in experimental diabetes. Diabetes 39, 10401044.Google Scholar