The Yale–Potsdam Stellar Isochrones (YaPSI) cover the low and intermediate stellar mass regime (0.15 to 5.0 M⊙) for a wide range of solar-scaled chemical compositions (metallicity from −0.5 to +0.3; helium mass fraction from 0.25 to 0.37, assigned independently of each other). The tracks are finely spaced in mass, to allow for accurate interpolation. The models feature state-of-the-art input physics relevant to low-mass stars modeling (surface boundary conditions, equation of state), thus updating the faint end of the Yonsei-Yale (YY) isochrones. Utility codes, such as an isochrone interpolator in age, metallicity and helium content, are also provided. The YaPSI isochrones are in good agreement with the empirical mass–luminosity and mass–radius relations available to date, and provide satisfactory fitting of the color-magnitude diagrams of well-studied open clusters.