We present our recent work on the conditions under which star formation occurs in a metal-poor environment, the Large Magellanic Cloud ([Fe/H] ~ −0.4). Water masers are used as beacons of the current star formation in H II regions. Comparing their location with the dust morphology imaged with the Spitzer Space Telescope, and additional Hα imaging and groundbased near-infrared observations, we conclude that the LMC environment seems favourable to sequential star formation triggered by massive star feedback (Oliveira et al. 2006). Good examples of this are 30 Doradus and N 113. There are also H II regions, such as N 105A, where feedback may not be responsible for the current star formation although the nature of one young stellar object (YSO) suggests that feedback may soon start making an impact. The chemistry in one YSO hints at a stronger influence from irradiation effects in a metal-poor environment where shielding by dust is suppressed (van Loon 2005).