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Influence of dietary fatty acids on the fatty acid composition of gut mucosa in calves during the first 3 weeks of life

  • K.N. Muturi (a1), M. Birnie (a1), M. Wallace (a1), J. Struthers (a1), J. R. Scaife (a1) and M.A. Lomax (a1)...


The balance between pro and anti-inflammatory elements of the immune system can be influenced by provision of specific dietary polyunsaturated fatty acids (PUFA) (Calder, 1998). The gut associated lymphoid tissue (GALT) is the largest immune organ and an important regulator of tolerance and sensitivity to dietary and environmental antigens in the gut (Harbige and Fisher, 2001). Changing the fatty acid composition of the gut mucosa could influence the immune function of the GALT. This study was carried out to establish the extent to which dietary n-3 or n-6 PUFA-rich oil supplements could change the fatty acid composition of gut mucosa of the neonatal calf.


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Calder, P.C. 1998. Modulation of immune function by dietary fatty acids, Proceedings of the Nutrition Society, 57: 277292.
Christie, W. W. (1982). Lipid Analysis, Second edition Pergamon Press, Oxford
Harbige, L.S. and Fisher, A.C. 2001. Dietary fatty acid modulation of mucosally induced tolerogenic immune response. Proceedings of the Nutrition Society. 60: 449456.


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