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The effect of exogenous prostaglandin F?? analogue administration on subsequent corpus luteum function in the dairy cow

Published online by Cambridge University Press:  20 November 2017

G.R. Starbuck
Affiliation:
University of Nottingham, School of Biological Sciences, Division of Animal Physiology, Sutton Bonington, Loughborough, Leicestershire LE12 5RD, UK
G.E. Mann
Affiliation:
University of Nottingham, School of Biological Sciences, Division of Animal Physiology, Sutton Bonington, Loughborough, Leicestershire LE12 5RD, UK
G.E. Lamming
Affiliation:
University of Nottingham, School of Biological Sciences, Division of Animal Physiology, Sutton Bonington, Loughborough, Leicestershire LE12 5RD, UK
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Extract

Historically there has been some controversy over possible detrimental effects of exogenous prostaglandin F? ? ? (PGF? ?) administration on the function of the subsequent corpus luteum (CL). In the light of recent evidence that early luteal phase progesterone is essential for embryonic development (Mann et al., 1996) combined with the clinical use of PGF2? analogues in herd fertility management, an urgent need has arisen for this matter to be clarified. This abstract presents work designed to investigate whether two of the commercially available PGF? ? analogues used in veterinary therapy have any detrimental effect on corpus luteum function.

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Copyright
Copyright © The British Society of Animal Science 1999

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References

Mann, G.E., Mann, S.J. & Lamming, G.E. (1996). The inter-relationship between the maternal hormone environment and the embryo during the early stages of pregnancy. Journal of Reproduction & Fertility Abstract Series No. 17; abstract 55.Google Scholar