Various studies in animals have shown conditioned responses toward food flavours created through their associations with positive or negative post-ingestive consequences (PIC). Essentially these studies presume a temporal contiguity, as necessary in permitting associations, and that flavours are a major determinant of such responses. It has been shown that associations between a novel food flavour and subsequent negative PIC can also be formed even when they are disassociated in time (long delay learning); no such evidence exists for this type of learning from positive PIC (Capaldi, 1992). In this study two objectives were tested: (i) whether such associations could be established with delays between consumption of a flavoured food and positive or negative PIC resulting from casein administration, and (ii) how these associations are affected by initial responses towards food flavours.