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The effect of high-fat diets on gastric inhibitory polypeptide (gip) and insulin secretion in growing pigs
Published online by Cambridge University Press: 24 November 2017
Extract
Hyperinsulinaemia, which is associated with obesity and type II diabetes (Gama and Marks, 1989), may be due in part to an overactive enteroinsular axis. The gut hormone GIP is a potent stimulator of insulin secretion and is currently thought to be one of the main components of the enteroinsular axis. Exaggerated GIP responses have been observed after a mixed meal in obese subjects (Hampton, Kwasowski, Tan, Morgan and Marks, 1983), and a high-fat diet increases fat-stimulated GIP secretion in rats (Ebert, Willms, Brown and Creutzfeldt, 1976) and glucose stimulated GIP secretion in man (Morgan, Tredger, Hampton, Kwasowski, Wright, Dunn and Marks, 1983). This experiment was designed to investigate the effects of high-fat diets on the development of the biochemical parameters which are characteristic of obesity.
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- Pig Production
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- Copyright
- Copyright © The British Society of Animal Production 1990