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X-ray powder diffraction data for alogliptin benzoate, C18H21N5O2·C7H6O2

Published online by Cambridge University Press:  15 December 2016

Xia Zeng ,
Qing Wang ,
Xin Nuo Xiong ,
Qiao Hong Du  and
Hui Li
Xia Zeng
Affiliation:
College of Chemical Engineering, Sichuan University, Chengdu 610065, China
Qing Wang
Affiliation:
College of Chemical Engineering, Sichuan University, Chengdu 610065, China
Xin Nuo Xiong
Affiliation:
College of Chemical Engineering, Sichuan University, Chengdu 610065, China
Qiao Hong Du
Affiliation:
College of Chemical Engineering, Sichuan University, Chengdu 610065, China
Hui Li*
Affiliation:
College of Chemical Engineering, Sichuan University, Chengdu 610065, China
*
a)Author to whom correspondence should be addressed. Electronic mail: lihuilab@sina.com
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Abstract

X-ray powder diffraction data, unit-cell parameters, and space group for alogliptin benzoate, C18H21N5O2·C7H6O2, are reported [a = 28.8260(8) Å, b = 9.9654(4) Å, c = 8.1477(8) Å, α = 90, β = 90, γ = 90°, unit-cell volume V = 2340.57 Å3, Z = 4, ρcal = 1.3097 g cm−3, and space group P212121]. All measured lines were indexed and are consistent with the P212121 space group, No detectable impurities were observed.

Keywords

X-ray powder diffractionalogliptin benzoate
Type
Data Reports
Information
Powder Diffraction , Volume 32 , Issue 1 , March 2017 , pp. 49 - 52
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Copyright
Copyright © International Centre for Diffraction Data 2016 

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References

Boultif, A. and Louër, D. (1991). “Indexing of powder diffraction patterns for low-symmetry lattices by the successive dichotomy method,” J. Appl. Crystallogr. 24, 987–993.CrossRefGoogle Scholar
de Wolff, P. M. (1968). “A simplified criterion for the reliability of a powder pattern,” J. Appl. Crystallogr. 1, 108–113.CrossRefGoogle Scholar
Feng, J., Zhang, Z., and Wallace, M. B. (Eds) (2007). “Discovery of alogliptin: a potent, selective, bioavailable, and efficacious inhibitor of dipeptidyl peptidase IV”, J. Med. Chem. 50, 2297–2300.CrossRefGoogle ScholarPubMed
Gelbrich, T., Griesser, U. J., and Kahlenberg, V. (2013). “Alogliptin and its benzoate salt,” J. Acta Crystallogr. 69, 674–678.Google ScholarPubMed
Li, S. S., Wu, X. Q., Pan, Q. Q., Cheng, Q., and Li, H. (2014). “Comparison of the accuracy of powder and single crystal X-ray diffraction techniques in determining organic crystal structure,” Chin. Sci. Bull. 59, 497–501.CrossRefGoogle Scholar
McIntosh, C. H. S., Demuth, H. U., Pospisilik, J. A., and Pederson, R. (2005). Dipeptidyl peptidase IV inhibitors: how do they work as new antidiabetic agents. J. Regul. Pept. 128, 159–165.CrossRefGoogle ScholarPubMed
Saisho, Y. (2015). “Alogliptin benzoate for management of type 2 diabetes”, J. Vasc. Health Risk Manage. 11, 229–243.CrossRefGoogle ScholarPubMed
Smith, G. S. and Snyder, R. L. (1979). “FN: a criterion for rating powder diffraction patterns and evaluating the reliability of powder indexing,” J. Appl. Crystallogr. 12, 60–65.CrossRefGoogle Scholar
Wang, Q., Sun, Q. M., Li, S. S., Guo, L. Q., and Li, H. (2015). “X-ray powder diffraction data for drospirenone, C24H30O3 ,” Powder Diffr. 31(1), 63–65.CrossRefGoogle Scholar
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