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Systematic temporal changes in host susceptibility to infection: demographic mechanisms

Published online by Cambridge University Press:  06 April 2009

H. I. McCallum  and
R. M. Anderson
H. I. McCallum
Affiliation:
Department of Pure and Applied Biology, Imperial College, London University, London SW7 2BB
R. M. Anderson
Affiliation:
Department of Pure and Applied Biology, Imperial College, London University, London SW7 2BB
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Summary

Simple mathematical models are developed to examine the influence of variability in host susceptibility to infection, on the dynamics of host–parasite population interactions. When hosts differ in their innate susceptibility (at birth), to infection by a specific parasite, the average susceptibility of the host population as a whole may show systematic changes through time. Such patterns may arise as a result of demographic factors associated with the interaction between host and parasite populations, in the absence of inheritance mechanisms (a genetic component) or acquired resistance (an immunological component). The general significance of this observation is discussed in terms of the coevolution of host–parasite associations.

Type
Research Article
Information
Parasitology , Volume 89 , Issue 1 , August 1984 , pp. 195 - 208
Copyright
Copyright © Cambridge University Press 1984

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