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Recent advances in the diagnosis, impact on production and prediction of Fasciola hepatica in cattle

Published online by Cambridge University Press:  07 November 2013

J. CHARLIER ,
J. VERCRUYSSE ,
E. MORGAN ,
J. VAN DIJK  and
D. J. L. WILLIAMS
J. CHARLIER*
Affiliation:
Department of Virology, Parasitology and Immunology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
J. VERCRUYSSE
Affiliation:
Department of Virology, Parasitology and Immunology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium
E. MORGAN
Affiliation:
School of Veterinary Science, University of Bristol, Langford House, Langford, North Somerset BS40 5DU, UK
J. VAN DIJK
Affiliation:
Department of Epidemiology and Population Health, Institute of Infection and Global Health, University of Liverpool, Leahurst, Neston, Cheshire CH64 7TE, UK
D. J. L. WILLIAMS
Affiliation:
Veterinary Parasitology, Institute of Infection and Global Health, University of Liverpool, 146 Brownlow Hill, Liverpool L3 5RF, UK
*
*Corresponding author: Department of Virology, Parasitology and Immunology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium. E-mail: johannes.charlier@ugent.be
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Summary

Fasciola hepatica is a pathogenic trematode parasite of ruminants with a global distribution. Here, we briefly review the current epidemiology of bovine fasciolosis in Europe and discuss the progress made over the last decade in the diagnosis, impact on production and prediction of F. hepatica in cattle. Advances in diagnosis have led to significantly improved coprological and serological methods to detect presence of infection. Diagnostic test results have been correlated with intensity of infection and associated production losses, unravelling the impact on carcass weight and milk yield in modern cattle production systems. The economic impact of fasciolosis may, however, go beyond the direct impacts on production as evidence shows that F. hepatica can modulate the immune response to some co-infections. Control of bovine fasciolosis remains hampered by the limitations of the currently available flukicidal drugs: few drugs are available to treat dairy cows, many have low efficacies against juvenile stages of F. hepatica and there is evidence for the development of drug resistance. This makes research into the prediction of risk periods, and thus the optimum application of available drugs more pertinent. In this field, the recent research focus has been on understanding spatial risk and delivering region-specific spatial distribution maps. Further advances in epidemiological and economic research on bovine fasciolosis are expected to deliver farm-specific economic assessments of disease impact, to leverage non-chemotherapeutic management options and to enhance a more targeted use of anthelmintics.

Keywords

Fasciola hepaticaruminantimmunityglobal changeanthelminticscontrol
Type
Invited Review
Information
Parasitology , Volume 141 , Issue 3 , March 2014 , pp. 326 - 335
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Copyright
Copyright © Cambridge University Press 2013 

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