Abath, FG, Coutinho, EM, Montenegro, SM, Gomes, YM and Carvalho, AB (1988) The use of non-specific immunopotentiators in experimental Trypanosoma cruzi infection. Transactions of the Royal Society of Tropical Medicine and Hygiene 82, 73–76.
Amery, WK and Bruynseels, JP (1992) Levamisole, the story and the lessons. International Journal of Immunopharmacology 14, 481–486.
Brener, Z (1962) Therapeutic activity and criterion of cure on mice experimentally infected with Trypanosoma cruzi. Revista do Instituto de Medicina Tropical de São Paulo 4, 386–396.
Brunner, CJ and Muscoplat, CC (1980) Immunomodulatory effects of levamisole. Journal of the American Veterinary Medical Association 176(10 ), 1159–1162.
Butler, PG (1982) Levamisole and immune response phenomena in cutaneous leishmaniasis. Journal of the American Academy of Dermatology 6, 1070–1077.
Chandrasekar, B, Melby, PC, Troyer, DA and Freeman, GL (1996) Induction of proinflammatory cytokine expression in experimental acute Chagasic cardiomyopathy. Biochemical and Biophysical Research Communications 223, 365–371.
Coura, JR (2009) Present situation and new strategies for Chagas disease chemotherapy: a proposal. Memórias do Instituto Oswaldo Cruz 104, 549–554.
Duffy, T, Cura, CI, Ramirez, JC, Abate, T, Cayo, NM, Parrado, R, Bello, ZD, Velazquez, E, Muñoz-Calderon, A, Juiz, NA, Basile, J, Garcia, L, Riarte, A, Nasser, JR, Ocampo, SB, Yadon, ZE, Torrico, F, de Noya, BA, Ribeiro, I and Schijman, AG (2013) Analytical performance of a multiplex real-time PCR assay using TaqMan probes for quantification of Trypanosoma cruzi satellite DNA in blood samples. PLoS Neglected Tropical Diseases 7, e2000.
Ferraz, ML, Gazzinelli, RT, Alves, RO, Urbina, JA and Romanha, AJ (2007) The anti-Trypanosoma cruzi activity of posaconazole in a murine model of acute Chagas' disease is less dependent on gamma interferon than that of benznidazole. Antimicrobial Agents and Chemotherapy 51, 1359–1364.
Filardi, LS and Brener, Z (1987) Susceptibility and natural resistance of Trypanosoma cruzi strains to drugs used clinically in Chagas disease. Transactions of the Royal Society of Tropical Medicine and Hygiene 81, 755–759.
Fredericks, C, Yon, JR, Alex, G, Morton, M, Messer, T, Bokhari, F and Poulakidas, S (2017) Levamisole-induced necrosis syndrome: presentation and management. Wounds 29, 71–76.
Gao, W and Pereira, MA (2002) Interleukin-6 is required for parasite specific response and host resistance to Trypanosoma cruzi. International Journal of Parasitology 32, 167–170.
Köksal, ZŞ, Yanik, K, Bilgin, K, Yılmaz, EM and Hokelek, M (2016) In vivo efficacy of drugs against Toxoplasma gondii combined with immunomodulators. Japanese Journal of Infectious Diseases 69, 113–117.
Libeau, G and Pinder, M (1981) Deleterious effect of levamisole on experimental trypanosomiasis in mice. Revue d’Élevage et de Médecine Vétérinaire des Pays Tropicaux 34, 399–404, .
Lionel, ND, Mirando, EH, Nanayakkara, JC and Soysa, PE (1969) Levamisole in the treatment of ascariasis in children. British Medical Journal 4, 340–341.
Maude, RJ, Silamut, K, Plewes, K, Charunwatthana, P, Ho, M, Abul Faiz, M, Rahman, R, Hossain, MA, Hassan, MU, Bin Yunus, E, Hoque, G, Islam, F, Ghose, A, Hanson, J, Schlatter, J, Lacey, R, Eastaugh, A, Tarning, J, Lee, SJ, White, NJ, Chotivanich, K, Day, NP and Dondorp, AM (2014) Randomized controlled trial of levamisole hydrochloride as adjunctive therapy in severe falciparum malaria with high parasitemia. Journal of Infectious Diseases 209, 120–129.
Morato, MJ, Colley, DG and Powell, MR (1998) Cytokine profiles during experimental Chagas’ disease. Brazilian Journal of Medical and Biological Research 31, 123–125.
Moreira, OC, Ramírez, JD, Velázquez, E, Melo, MF, Lima-Ferreira, C, Guhl, F, Sosa-Estani, S, Marin-Neto, JA, Morillo, CA and Britto, C (2013) Towards the establishment of a consensus real-time qPCR to monitor Trypanosoma cruzi parasitemia in patients with chronic Chagas disease cardiomyopathy: a substudy from the BENEFIT trial. Acta Tropica 125, 23–31.
Morillo, CA, Waskin, H, Sosa-Estani, S, Del Carmen Bangher, M, Cuneo, C, Milesi, R, Mallagray, M, Apt, W, Beloscar, J, Gascon, J, Molina, I, Echeverria, LE, Colombo, H, Perez-Molina, JA, Wyss, F, Meeks, B, Bonilla, LR, Gao, P, Wei, B, McCarthy, M, Yusuf, S and STOP-CHAGAS Investigators. (2017) Benznidazole and posaconazole in eliminating parasites in asymptomatic T. cruzi carriers: The STOP-CHAGAS Trial. Journal of the American College of Cardiology 69, 939–947.
Mutch, RS and Hutson, PR (1991) Levamisole in the adjuvant treatment of colon cancer. Clinical Pharmacology 10, 95–109.
Nabors, GS and Tarleton, RL (1991) Differential control of IFN-gamma and IL-2 production during Trypanosoma cruzi infection. Journal of Immunology 146, 3591–3598.
Prata, A (2001) Clinical and epidemiological aspects of Chagas disease. The Lancet Infectious Diseases 1, 92–100.
Rassi, AJ, Rassi, A and Marin-Neto, A (2010) Chagas disease. The Lancet 375, 1388–1402.
Rezai, HR, Behbehani, AB, Gettner, S and Ardehali, S (1988) Effect of levamisole on the course of experimental leishmaniasis in Guinea-pigs and mice: haematological and immunological findings. Annals of Tropical Medicine & Parasitology 82, 243–249.
Renoux, G (1980) The general immunopharmacology of levamisole. Drugs 20, 89–99.
Rifaat, LK, Mohammad, MA and Jawdat, SZ (1989) Ivermectin, levamisole and thymic extract for chemotherapy and immunostimulation of visceral leishmaniasis in hamsters and mice. Japanese Journal of Medical Science and Biology 42, 51–61.
Risvanli, A and Aydin, M (2003) The effects of levamisole on the pregnancy rate, average litter size, sexuality, living rate and lactation period in rats. Firat University Journal of Health Sciences (Turkey) 17, 45–47.
Scarim, CB, Jornada, DH, Chelucci, RC, de Almeida, L, Dos Santos, JL and Chung, MC (2018) Current advances in drug discovery for Chagas disease. European Journal of Medicinal Chemistry 155, 824–838.
Scherb, J (1969) Therapeutic efficiency of levamisole in human ascariasis. Hospital (Rio J) 76, 1067–1070, .
Simões-Silva, MR, De Araújo, JS, Oliveira, GM, Demarque, KC, Peres, RB, D'Almeida-Melo, I, Batista, DGJ, Da Silva, CF, Cardoso-Santos, C, Da Silva, PB, Batista, MM, Bahia, MT and Soeiro, MNC (2017) Drug repurposing strategy against Trypanosoma cruzi infection: in vitro and in vivo assessment of the activity of metronidazole in mono- and combined therapy. Biochemical Pharmacology 145, 46–53.
Torrico, F, Gascon, J, Ortiz, L, Alonso-Vega, C, Pinazo, MJ, Schijman, A, Almeida, IC, Alves, F, Strub-Wourgaft, N, Ribeiro, I and E1224 Study Group (2018) Treatment of adult chronic indeterminate Chagas disease with benznidazole and three E1224 dosing regimens: a proof-of-concept, randomised, placebo-controlled trial. Lancet Infectious Diseases 18, 419–430.
Truyens, C, Angelo-Barrios, A, Torrico, F, Van Damme, J, Heremans, H and Carlier, Y (1994) Interleukin-6 (IL-6) production in mice infected with Trypanosoma cruzi: effect of its paradoxical increase by anti-IL-6 monoclonal antibody treatment on infection and acute-phase and humoral immune responses. Infectious Immunology 62, 692–696.