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Immunocytochemical demonstration of a neuropeptide in Ascaris suum (Nematoda) using an antiserum to FMR Famide

Published online by Cambridge University Press:  06 April 2009

T. R. B. Davenport ,
D. L. Lee  and
R. E. Isaac
T. R. B. Davenport
Affiliation:
Department of Pure and Applied Biology, University of Leeds, Leeds LS2 9JT
D. L. Lee
Affiliation:
Department of Pure and Applied Biology, University of Leeds, Leeds LS2 9JT
R. E. Isaac
Affiliation:
Department of Pure and Applied Biology, University of Leeds, Leeds LS2 9JT
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Summary

A FMRFamide-like peptide has been detected in the nematode Ascaris suum, using the peroxidase-anti-peroxidase (PAP) immunocytochemical technique. Positive reactions were obtained in both the central nervous system and the peripheral nervous system of the worm, the strongest reactions being in the anterior nerve ring, the cephalic papillary ganglia, the lateral ganglia and the dorso-rectal ganglion. Immunoreactivity was observed along the length of the main nerve cords of the worm and, to a lesser extent, in the pharyngeal nerve cords. The possible role of this neuropeptide in the physiology of the nematode is discussed.

Type
Research Article
Information
Parasitology , Volume 97 , Issue 1 , August 1988 , pp. 81 - 88
Copyright
Copyright © Cambridge University Press 1988

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