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Aldose reductase and sorbitol dehydrogenase in the muscle of Ascaris suum (Nematoda)

Published online by Cambridge University Press:  06 April 2009

M. M. Goil  and
R. P. Harpur
M. M. Goil
Affiliation:
Institute of Parasitology, McGill University, Macdonald College Post Office, P.Q., Canada HOA 1CO
R. P. Harpur
Affiliation:
Institute of Parasitology, McGill University, Macdonald College Post Office, P.Q., Canada HOA 1CO
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Summary

The muscle of Ascaris suum contains sorbitol dehydrogenase [EC 1.1.1. 14] and the apparent Km values indicate that the enzymefavours fructose formation. Aldose reductase [EC 1.1.1.21] is also present and like the mammalian enzyme it has a very high apparent Km for glucose. Possible functions of the sorbitol pathway in Ascaris muscle are discussed.

Type
Research Article
Information
Parasitology , Volume 77 , Issue 1 , August 1978 , pp. 97 - 102
Copyright
Copyright © Cambridge University Press 1978

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