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An association between schistosomes and contrapsin, a mouse serine protease inhibitor (serpin)

Published online by Cambridge University Press:  06 April 2009


J. Modha
Affiliation:
Department of Medical Helminthology, London School of Hygiene and Tropical Medicine, Winches Farm Field Station, 395 Hatfield Boad, St Albans AL4 0XQ
Vaishu Parikh
Affiliation:
Department of Medical Helminthology, London School of Hygiene and Tropical Medicine, Winches Farm Field Station, 395 Hatfield Boad, St Albans AL4 0XQ
J. Gauldie
Affiliation:
Department of Pathology, McMaster University, Hamilton, Ontario, CanadaL8N 3Z5
M. J. Doenhoff
Affiliation:
Department of Medical Helminthology, London School of Hygiene and Tropical Medicine, Winches Farm Field Station, 395 Hatfield Boad, St Albans AL4 0XQ

Summary

An antigen in homogenates of adult Schistosoma mansoni worms grown in mice, and immunoprecipitated by polyspecific rabbit antiserum, has been identified as contrapsin, a mouse serine protease inhibitor (serpin). In the serum of some mice infected with S. mansoni contrapsin was found with altered immunoelectrophoretic characteristics when compared with contrapsin from uninfected mice.


Type
Research Article
Copyright
Copyright © Cambridge University Press 1988

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References

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