Hope is a multi-dimensional concept that is integral to a dying person's needs. It is an essential resource that assists individuals with a life-threatening illness to cope during times of intense physical and psychological distress. The objective of this article is to explore and analyze the therapeutic value of hope. The phenomenon of hope will be explored through the analysis and application of Dufault and Martocchio's Multidimensional Model of Hope (MMH) to a clinical scenario. Factors determining hope in cancer patients as well as interventions that can foster hope in dying patients will be identified. Discussion includes examination of literature gaps, relevance to nursing practice, and practical strategies to engender hope and thereby enhance quality of life (QOL) in advanced cancer patients.