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Health-related quality of life of patients on antiretroviral treatment in Botswana: A cross-sectional study

Published online by Cambridge University Press:  12 August 2016

Nnamdi O. Ndubuka ,
Hyun J. Lim ,
Valerie J. Ehlers  and
Dirk M. van der Wal
Nnamdi O. Ndubuka
Affiliation:
University of South Africa, Pretoria, Republic of South Africa Northern Inter-Tribal Health Authority, Prince Albert, Saskatchewan, Canada
Hyun J. Lim
Affiliation:
University of Saskatchewan, Saskatoon, Saskatchewan, Canada
Valerie J. Ehlers*
Affiliation:
University of South Africa, Pretoria, Republic of South Africa
Dirk M. van der Wal
Affiliation:
University of South Africa, Pretoria, Republic of South Africa
*
Address correspondence and reprint requests to: Valerie J. Ehlers, P.O. Box 65075, Erasmusrand, Pretoria 0165, Republic of South Africa. E-mail: ehlersjh@mweb.co.za.
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Abstract

Objective:

Antiretroviral therapy (ART) affords longevity to patients infected with the human immune deficiency virus (HIV). Since little is known about the health-related quality of life (HRQoL) of persons who have been on ART for at least five years, the present study investigated the HRQoL of these patients in Botswana.

Method:

Medical records, structured interviews, and the World Health Organization Quality of Life–BREF (WHOQoL–HIV–BREF) instrument were employed to obtain information from 456 respondents.

Results:

Univariate and multivariate regression analyses showed that respondents' highest scores were in the “physical” domain (mean = 15.8, SD = 3.5), while the lowest scores were in the “environment” domain (mean = 12.9, SD = 2.5). Thus, the physical domain had the greatest impact on patients' overall HRQoL. Self-education about HIV-related issues was significantly correlated with all domains of HRQoL scores: physical (ρ = –2.32, CI95% = –3.02, –1.61); psychological (ρ = –2.26, CI95% = –2.87, –1.65); independence (ρ = –1.81, CI95% = –2.54, –1.06); social relationships (ρ = –1.40, CI95% = –2.13, –0.67); environment (ρ = –1.58, CI95% = –2.13, –1.04); and spirituality (ρ = –1.70, CI95% = –82.27, –1.13).

Significance of results:

HRQoL assessments can identify and address patients' needs, and it is important that guidelines be developed that will yield improved care to ART patients in Botswana.

Keywords

Antiretroviral therapyHealth-related quality of lifeHRQoLHIV/AIDSWHOQoL–HIV–BrefBotswana
Type
Original Articles
Information
Palliative & Supportive Care , Volume 15 , Issue 2 , April 2017 , pp. 214 - 222
Copyright
Copyright © Cambridge University Press 2016 

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