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Viscoelastic Properties of Healthy Human Artery Measured in Saline Solution by AFM-Based Indentation Technique

Published online by Cambridge University Press:  15 February 2011

A. Lundkvist ,
E. Lilleodden ,
W. Siekhaus ,
J. Kinney ,
L. Pruitt  and
M. Balooch
A. Lundkvist
Affiliation:
University of California, Berkeley CA 94720
E. Lilleodden
Affiliation:
Lawrence Livermore National Laboratory, Livermore CA 94550, baloochl @llnl.gov
W. Siekhaus
Affiliation:
Lawrence Livermore National Laboratory, Livermore CA 94550, baloochl @llnl.gov
J. Kinney
Affiliation:
Lawrence Livermore National Laboratory, Livermore CA 94550, baloochl @llnl.gov
L. Pruitt
Affiliation:
University of California, Berkeley CA 94720
M. Balooch
Affiliation:
Lawrence Livermore National Laboratory, Livermore CA 94550, baloochl @llnl.gov
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Abstract

Using an Atomic Force Microscope with an attachment for indentation, we have measured local, in vitro mechanical properties of healthy femoral artery tissue held in saline solution. The elastic modulus (34.3 kPa) and viscoelastic response (τɛ = 16.9 s and τσ = 29.3 s) of the unstretched, intimal vessel wall have been determined using Sneddon theory and a three element model (standard linear solid) for viscoelastic materials. The procedures necessary to employ the indenting attachment to detect elastic moduli in the kPa range in liquid are described.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 436: Symposium CC – Thin Films Stresses and Mechanical Properties VI , 1996 , 353
Copyright
Copyright © Materials Research Society 1997

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