Single phase orthorhombic YBa2(Cuy1−xZnx)3O7 samples were formed for 0<x<0.16. The high T superconductivityXfor x=6 (T =90 K) is rapidly depressed with increasing x, and is quenched for x>0.08. Low field (<100 G) cooled magnetization studies show that the superconducting component decreases as x approaches the critical value for suppression of superconductivity, and this is supported by high resolution specific heat measurements in the vicinity of T. Temperature dependent electrical resistivity studies for x<0.08 show metallic behavior; for x>0.10 semiconducting behavior. The electrical resistance was studied at high quasihydrostatic pressures also, and for x=0.08 showed that T is depressed with increasing pressure: T → 0 K for P >10 GPa. This is in°contrast to YBa2(Cuy1−xZnx)3O7 where dT /dP>0. The data support evidence for the high sensitivity to chemical and ice perturbations of the physical properties of samples near the superconducting-normal transition region.