Skip to main content Accessibility help

Synthesis and Cytotoxicity of Luminescent InP Quantum Dots

  • Yuxuan Wang (a1), Chai Hoon Quek (a2), Kam W. Leong (a3) and Jiye Fang (a4)


As a potential biological imaging probe with a long-wavelength of emission, InP quantum dots were prepared via a high-temperature organic solution approach, and successfully transferred into an aqueous system through a ligand-exchange process using various functional surfactants. Photoluminescence and X-ray characterizations confirmed the desired properties of the InP quantum dots. The cytotoxicity of the water-soluble InP quantum dots against phaeochromocytoma PC12 cells as evaluated by the MTS cell viability assay was low relative to a positive control, poly(ethyleneimine). This study suggests a bright potential for this new type of InP quantum dots in bioimaging applications.



Hide All
1 Bruchez, M. Jr. , Moronne, M. Gin, P. Weiss, S. Alivisatos, A. P. Science 281, 20132016 (1998).
2 Kim, S. Lim, Y. T. Soltesz, E. G. A. M. De Grand, Lee, J. Nakayama, A. Parker, J. A. Mihaljevic, T., Laurence, R. G. Dor, D. M. Cohn, L. H. Bawendi, M. G. Frangioni, J. V. Nat. Biotechnol. 22, 9397 (2004).
3 Michalet, X. Pinaud, F. F. Bentolila, L. A. Tsay, J. M. Doose, S. Li, J. J. Sundaresan, G. Wu, A. M. Gambhir, S. S. Weiss, S. Science 307, 538544 (2005).
4 Colvin, V. L. Schlamp, M. C. Allvisatos, A. P. Nature 370, 354357 (1994).
5 Klimov, V. I. Mikhailovsky, A. A. Xu, S. Malko, A. Hollingsworth, J. A. Leatherdale, C. A., Eisler, H.J. Bawendi, M. G. Science 290, 314317 (2000).
6 Micic, O. I. Sprague, J. R. Curtis, C. J. Jones, K. M. Machol, J. L. Nozik, A. J. Giessen, H., Fluegel, B. Mohs, G. Peyghambarian, N. J. Phys. Chem. 99, 77547759 (1995).
7 Guzelian, A. A. Katari, J. E. B. Kadavanich, A. V. Banin, U. Hamad, K. Juban, E. Alivisatos, A. P., Wolters, R. H. Arnold, C. C. Heath, J. R. J. Phys. Chem. 100, 72127219 (1996).
8 Battaglia, D. Peng, X. Nano Lett. 2, 10271030, (2002).
9 Xu, S. Kumar, S. Nann, T. J. Am. Chem. Soc. 128, 10541055 (2006).
10 Liu, Z. Kumbhar, A. Xu, D. Zhang, J.; Sun, Z. Fang, J. Angew. Chem. Int. Ed. 47, 35403542, (2008).
11 Ahrenkiel, S. P. Micic, O. I. Miedaner, A. Curtis, C. J. Nedeljkovic, J. M. Nozik, A. J. Nano Lett. 3, 833837 (2003).
12 Yong, K. T. Ding, H. Roy, I. Law, W. C. Bergey, E. J. Maitra, A. Prasad, P. N. ACS Nano, 3 (3), 502510 (2009)
13 Xie, R. Battaglia, D. Peng, X. J. Am. Chem. Soc. 129, 1543215433 (2007).
14 Xie, J. Xu, C. Xu, Z. Hou, Y. Young, K. Wang, S. Pourmand, N. Sun, S. Chem. Mater. 18, 54015403 (2006)
15 Wiepz, G. J. Edwin, F. Patel, T. Bertics, P. J. Methods Mol. Biol. 327, 179187 (2006).



Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed