The structural, mechanical and tribological properties of MoS2/metal and MoS2/carbide multilayer thin films have been examined in this study. The films were deposited by pulsed laser deposition of sequential layers of MoS2 and either Ti, Cr or TiC. The compositions of the films were analyzed by wavelength dispersive spectroscopy (WDS) and confirmed the presence of the deposited elements. X-ray diffraction and cross-section SEM methods were employed to characterize the films. The XRD results did not reveal the presence of separate Ti, Cr or TiC phases, and the SEM did not show any multilayer structures. From these results, it was concluded that the added metal or carbide elements are present as either a dispersed nano-structured phase or in solid solution with the MoS2. Nonetheless, friction and wear testing showed dramatic improvements over MoS2 films when tested in a humid (45% r/h) environment.