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Searching for Smart Durable Coatings to Promote Bone Marrow Stromal Cell Growth While Preventing Biofilm Formation

  • Fereydoon Namavar (a1), John D. Jackson (a2), J. Graham Sharp (a3), Ethan E. Mann (a4), Kenneth Bayles (a5), Barry Chin Li Cheung (a6), Connie A Feschuk (a7), Shailaja Varma (a8), Hani Haider (a9) and Kevin L. Garvin (a10)...

Abstract

There is a great need to develop methods to regulate cellular growth in order to enhance or prevent cell proliferation as needed, to either improve health or prevent disease. In this work we evaluated the adhesion, survival and growth of bone marrow stromal cells on the surface of several new ion beam engineered nano-crystals of ceramic hard coatings such as zirconium, titanium, tantalum and cerium oxides. Cell adhesion and growth on the ceramic coatings were compared to adhesion and growth on a nano-crystalline silver coating which is known to possess antibacterial properties. The initial results of a study to determine the effect of nanocrystalline titanium and silver coating on staphylococcus aureus biofilm growth is also discussed.

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Keywords

Searching for Smart Durable Coatings to Promote Bone Marrow Stromal Cell Growth While Preventing Biofilm Formation

  • Fereydoon Namavar (a1), John D. Jackson (a2), J. Graham Sharp (a3), Ethan E. Mann (a4), Kenneth Bayles (a5), Barry Chin Li Cheung (a6), Connie A Feschuk (a7), Shailaja Varma (a8), Hani Haider (a9) and Kevin L. Garvin (a10)...

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