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Polymerizable Self-Organized Membranes: A Novel Class of Organic Compounds

Published online by Cambridge University Press:  15 February 2011

Alok Singh ,
Michael Markowitz  and
Gan Moog Chow
Alok Singh
Affiliation:
Center for Bio/Molecular Science and Engineering, Code 6900, Naval Research Laboratory, Washington DC. 20375-5348
Michael Markowitz
Affiliation:
Center for Bio/Molecular Science and Engineering, Code 6900, Naval Research Laboratory, Washington DC. 20375-5348
Gan Moog Chow
Affiliation:
Center for Bio/Molecular Science and Engineering, Code 6900, Naval Research Laboratory, Washington DC. 20375-5348
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Abstract

Molecular Self-assembly of amphiphilic phospholipid molecules (containing a hydrophobic acyl chain and a hydrophilic phosphate group attached to glycerol backbone) and other amphiphiles offers a versatile approach to form ordered structures. Stabilization of lipid microstructures by polymerization renders them useful for practical applications in the areas ranging from controlled release technology to template mediated synthesis of metals. Our efforts are focussed on the development and use of polymerizable diacetylenic phospholipids and their microstructures as template for chemical synthesis. The surface of vesicles and lipid microcylinders (0.5 μm dia.) is made reactive by chemically modifying the hydrophilic region of phospholipids. Lipids with chemically reactive sites were incorporated into lipid membranes predominantly formed from charge neutral lipids and used for binding metal ions and growing fine metal particles.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 351: Symposium V – Molecularly Designed Ultrafine/Nanostructured Materials , 1994 , 67
Copyright
Copyright © Materials Research Society 1994

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References

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