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Phase Transformations Induced by Grinding: What is Revealed by Molecular Materials

  • Marc Descamps (a1), Jean François Willart (a2), Emeline DUDOGNON (a3), Ronan LEFORT (a4), Sylvain DESPREZ (a5) and Vincent CARON (a6)...

Abstract

The purpose of this paper is to show some examples of phase transformations induced by grinding molecular materials. These materials are considered because they are extremely sensitive to external disturbances and are generally very good glass formers. This allows investigating more easily a broad range of the parameters which are open to influence the nature of the end product namely the temperature and intensity of grinding. Such an investigation has also a practical interest in pharmaceutical science. It is shown that the position of the grinding temperature with regard to the glass transition temperature of the compound is a key parameter. Comparison of the effects of temperature and intensity of grinding demonstrates that the driven material concept offers a framework to rationalize all the observed transformations.

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Keywords

Phase Transformations Induced by Grinding: What is Revealed by Molecular Materials

  • Marc Descamps (a1), Jean François Willart (a2), Emeline DUDOGNON (a3), Ronan LEFORT (a4), Sylvain DESPREZ (a5) and Vincent CARON (a6)...

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