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Patterning of Cell Attachment to Biocompatible Glassy Polymeric Carbon by Silver Ion Implantation

Published online by Cambridge University Press:  01 February 2011

Robert Lee Zimmerman ,
Ismet Gurhan ,
Daryush Ila ,
F. Ozdal-Kurt ,
B. H. Sen  and
M. Rodrigues
Robert Lee Zimmerman
Affiliation:
rlzimm@cim.aamu.edu, Alabama A&M University, PO Box 313, 4900 Meridian St., Buchanan Way, Carnegie Bldg., Normal, AL, 35762-0313, United States
Ismet Gurhan
Affiliation:
ismetgurhan@yahoo.com, Ege University Faculty of Engineering, Izmir, N/A, Turkey
Daryush Ila
Affiliation:
ila@cim.aamu.edu, Alabama A&M University, Normal, Alabama, 35762, United States
F. Ozdal-Kurt
Affiliation:
OKurt@cbu.fs.ty, CBU, Faculty of Science, Manisa, N/A, N/A, Turkey
B. H. Sen
Affiliation:
bhs@eu.fd.ty, EU, Faculty of Dentistry, Izmir, N/A, 65412, Turkey
M. Rodrigues
Affiliation:
marcelo@dfm.usp.br, University of São Paulo, Ribeirão Preto, SP, N/A, Brazil
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Abstract

Although Glassy Polymeric Carbon (GPC) is ideally suited for implants in the blood stream, tissue that normally forms around the moving parts of a GPC heart valve. There is concern that the tissue lose adhesion and create the condition for embolisms downstream. We have shown that silver ion implantation or argon ion assisted surface deposition of silver inhibits cell growth on GPC, a desirable improvement of current cardiac implants. In vitro biocompatibility tests have been carried out with model cell lines to demonstrate that near surface implantation of silver in GPC can completely inhibit cell attachment on implanted areas while leaving adjacent areas unaffected. Patterned ion implantation permits precise control of tissue growth on medical applications of GPC.

Keywords

biomedicaladhesionC
Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 942: Symposium W – Colloidal Materials – Synthesis, Structure, and Applications , 2006 , 0942-W11-28
Copyright
Copyright © Materials Research Society 2006

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