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One-Step Microwave-Assisted Aqueous Synthesis of Silver-Based Nanoparticles Functionalized by Glutathione

Published online by Cambridge University Press:  10 September 2014

Myrna Reyes Blas ,
Maricely Ramírez-Hernandez ,
Danielle Rentas ,
Oscar Perales-Perez  and
Felix R. Román
Myrna Reyes Blas
Affiliation:
Department of Chemistry, University of Puerto Rico (UPRM), Mayaguez, USA
Maricely Ramírez-Hernandez
Affiliation:
Department of Chemical Engineering, University of Puerto Rico (UPRM), Mayaguez, USA,
Danielle Rentas
Affiliation:
Department of Chemistry, University of Puerto Rico (UPRM), Mayaguez, USA
Oscar Perales-Perez
Affiliation:
Department of Chemistry, University of Puerto Rico (UPRM), Mayaguez, USA Department of Engineering Science & Materials, UPRM, Mayaguez, USA
Felix R. Román
Affiliation:
Department of Chemistry, University of Puerto Rico (UPRM), Mayaguez, USA
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Abstract

The use of nano-sized silver and its alloys represents an interesting alternative to common food preservation methods, which are based on radiation, heat treatment and low temperature storage. These metal nanoparticles, embedded within a polymeric matrix for instance, would extend the shelf life of perishable foods while acting as a bactericidal agent to prevent food-borne illnesses. Common methods used in the synthesis of metal nanoparticles require toxic solvents and reagents that could be harmful to health and the food itself. In addition, several steps are required to obtain aqueous stable, i.e. dispersible, silver nanoparticles. In this work we propose the microwave-assisted aqueous synthesis of silver-based nanoparticles, (Ag Based NP) functionalized by glutathione (GSH) in a single-step using sodium sulfite (Na2SO3), as reducing agent. Ag-Based nanoparticles were synthesized at pH 6 and 1:3:1 (AgNO3/GSH/ Na2SO3) molar ratio. UV-Vis measurement clearly showed the plasmon peak attributed to silver-based nanoparticles (374 nm). Highly monodispersed water stable Ag-based nanoparticles were observed and 3.897 ± 0.167 nm particle size was determined through Transmission Electron Microscopy. FT-IR measurements suggested the actual GSH-Ag based surface interaction through –SH and –COOH groups; the functionalization by GSH explained the high stability of the nanoparticles in aqueous suspensions. These Ag-GSH nanoparticles exhibited remarkable antimicrobial activity against E. Coli.

Keywords

Agnanoscaletransmission electron microscopy (TEM)
Type
Articles
Information
MRS Online Proceedings Library (OPL) , Volume 1675: Symposium K/RR – Synthesis, Characterization and Applications of Functional Materials—Thin Films and Nanostructures , 2014 , pp. 163 - 168
Copyright
Copyright © Materials Research Society 2014 

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References

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