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On the Development of Biomimetic Sensors: Immobilizaton of Lipid Bilayers in Layered Ceramics

  • Michael W. Russell (a1), Vivek Mehrotra (a1) and Emmanuel P. Giannelis (a1)


Artificial membranes possessing physicochemical properties similar to biological membranes have been synthesized by immobilization of synthetic amphiphiles in layered ceramics. The intercalated bilayer-forming amphiphiles exhibit a gallery height of about 39 Å. Retention of bilayer-forming characteristics is further confirmed by the presence of a crystal to liquid-crystal phase transition. A dramatic increase in the membrane capacitance at the tansition temperature is attributed to an increase in membrane fluidity.



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