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Medical-Grade Polyurethanes: Their Crucial Role in Artificial Hearts

Published online by Cambridge University Press:  26 February 2011

Michael Szycher*
Affiliation:
V. P. Research, Thermedics Inc., 470 Wildwood Street, Woburn, MA 01888
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Extract

One of the most crucial requirements since the inception of the artificial heart program has been the need to develop biomaterials specific to chronic implantation. Major problems include the propensity for thrombus formation at the blood-materials interface, long-term flexing reliability, and the tendency of the body to reject foreign objects.

Type
Research Article
Copyright
Copyright © Materials Research Society 1988

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References

Bernhard, W.F.; LaFarge, C.G.; Liss, R.H.; Szycher, M.; Berger, R.L.; Poirier, V.L. “An Appraisal of Blood Trauma and the Blood-Prosthetic Interface During Left Ventricular Bypass in the Calf and Man”; Presented at the Annual Meeting of the Society of Thoracic Surgeons, Orlando, FL. Jan. 1978.Google Scholar
Bernhard, W.F.; LaFarge, C.G., Carr, J.G., J. Thor. Card. Surg. 1975, 70 (5), 880895.CrossRefGoogle Scholar
Bernhard, W.F.; Poirier, V.L.; Carr, J. “A Paracorporeal Left Ventricular Assist Device”; “Modern techniques in Surgery; Cardiac/Thoracic Surgery”; Futura Publishing Co., 1979.Google Scholar
Poirier, V.L.; Szycher, M., Whalen, R., Trans. Am. Soc. Artif. Intern. Organs, 1979, 25, 319324.CrossRefGoogle Scholar
Szycher, M.; Poirier, V.L.; Dempsey, D., “Advances in Textured Blood Interfaces”, Proceedings, 38th Annual Tech. Conf., SPE, XXVI, 1980, p. 662.Google Scholar
Szycher, M., “Clinical Needs for Synthetic Polymers in Critical Care Devices”, Keynote Address, ACS Symposium Innovation in Medical and Pharmaceutical Uses of Rubber, Chicago, Oct. 1982.Google Scholar
Szycher, M.; Bernhard, W.F., Poirier, V.L.; Franzblau, C.; Haudenschild, C., C. Trans. Am. Soc. Artif. Intern. Organs, 1980, 26, 493.Google Scholar
Szycher, M.; Poirier, V.L.; Dempsey, D., “Synthetic Polymers: Their Crucial Roles in Artificial Hearts”, JACS, Annual Meeting, Rubber Division, Chicago, 1982.Google Scholar
Szycher, M.; Daly, B.D.T.; Dasse, K., “Tissue/Porous Biomaterials Adherence: An Experimental Protocol:, Chapter in “Biomaterials in Reconstructive Surgery”; Rubin, L.R.; Mosby, C.V., Ed.; 1983.Google Scholar