Skip to main content Accessibility help
×
Home

MAPLE Direct Write (DW) patterning of Bio-active Ceramic Nanocomposites

  • A. Doraiswamy (a1), T. M. Patz (a1), R. J. Narayan (a1), L. Harris (a2), R. Auyeung (a2), R. Modi (a2) and D. B. Chrisey (a2)...

Abstract

A laser-based approach, Matrix Assisted Pulsed Laser Direct Write (MAPLE) technique is used to demonstrate two-dimensional direct writing of ceramics such as hydroxyl-apatite and zirconia, for developing inorganic scaffolds. We also demonstrate the patterning of live MG63 osteoblast cells onto various substrates. Our results show successful direct writing of ceramics and live cells concurrently, with a growth profile similar to that of as-deposited cells. After several days of growth, a live/dead assay shows live cells suggesting the biocompatibility of the ceramic and the viability of the process. This investigation demonstrates a novel method of developing heterogeneous tissue scaffolds, such as a cell-ceramic composite by CAD/CAM patterns.

Copyright

References

Hide All
1. Chrisey, D.B. et al, Chem. Rev. 103 553576 (2003).
2. Chrisey, D.B. et al, Applied Surface Science 168 345352 (2000).
3. Chrisey, D.B. et al, Applied Surface Science 154–155 593600 (2000).
4. Barron, J.A. et al, Appl. Phys. A 79, 10271030 (2004).
5. Ringeisen, B.R. et al, Tissue Engineering, Vol. 10, No. 3/4, (2004).
6. Wu, P.K. et al, Review of Scientific Instruments, Vol. 74. No.4, April (2003).
7. Ball, M.D., Biomaterials, 22 337347 (2001).

MAPLE Direct Write (DW) patterning of Bio-active Ceramic Nanocomposites

  • A. Doraiswamy (a1), T. M. Patz (a1), R. J. Narayan (a1), L. Harris (a2), R. Auyeung (a2), R. Modi (a2) and D. B. Chrisey (a2)...

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed