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High-Speed Photography of Human Trabecular Bone during Compression

  • Philipp J. Thurner (a1), Blake Erikson (a1), Zachary Schriock (a1), John Langan (a2), Jeff Scott (a2), Maria Zhao (a2), Georg E. Fantner (a1), Patricia Turner (a1), Johannes H. Kindt (a1), Georg Schitter (a1) and Paul K. Hansma (a1)...

Abstract

The mechanical properties of healthy and diseased bone tissue are extensively studied in mechanical tests. Most of this research is motivated by the immense costs of health care and social impacts due to osteoporosis in post-menopausal women and the aged. Osteoporosis results in bone loss and change of trabecular architecture, causing a decrease in bone strength. To address the problem of assessing local failure behavior of bone, we combined mechanical compression testing of trabecular bone samples with high-speed photography. In this exploratory study, we investigated healthy, osteoarthritic, and osteoporotic human vertebral trabecular bone compressed at high strain rates simulating conditions experienced in individuals during falls. Apparent strains were found to translate to a broad range of local strains. Moreover, strained trabeculae were seen to whiten with increasing strain. We hypothesize that the effect seen is due to microcrack formation in these areas, similar to stress whitening seen in synthetic polymers. From the results of a motion energy filter applied to the recorded movies, we saw that the whitened areas are, presumably, also of high deformation. We believe that this method will allow further insights into bone failure mechanisms, and help toward a better understanding of the processes involved in bone failure.

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1 Keaveny, T.M. and Hayes, W.C., J Biomech Eng 115 (4B), 534 (1993).
2 Melton, L. J., 3rd, Chrischilles, E. A., Cooper, C. et al., Journal of Bone and Mineral Research 7 (9), 1005 (1992); J. A. Kanis, Neth J Med 50 (5), 198 (1997).
3 Muller, R., Gerber, S. C., and Hayes, W. C., Technol Health Care 6 (5-6), 433 (1998).
4 Bay, B. K., Smith, T. S., Fyhrie, D. P. et al., Experimental Mechanics 39 (3), 217 (1999).
5 Nicolella, D. P., Nicholls, A. E., Lankford, J. et al., Journal of Biomechanics 34 (1), 135 (2001).
6 Nazarian, A. and Muller, R., J Biomech 37 (1), 55 (2004).
7 Thurner, P., Wyss, P., Voide, R. et al., in Developments in X-Ray tomography IV, edited by Bonse, U. (Denver, Colorado, 2004), Vol. 5535, pp. 112.
8 Currey, J. D., Bones: Structure and Mechanics. (Princeton University Press, Princeton, 2002).
9 Bay, B. K., J Orthop Res 13 (2), 258 (1995).
10 Adelson, E. H. and Bergen, J. R., Journal of the Optical Society of America a-Optics Image Science and Vision 2 (2), 284 (1985).
11 Odgaard, A., Hvid, I., and Linde, F., J Biomech 22 (8-9), 829 (1989).
12 Bonfield, W. and Grynpas, M. D., Journal of Biomechanics 15 (8), 555 (1982).
13 Osvalder, A. L., Neumann, P., Lovsund, P. et al., Journal of Biomechanics 26 (10), 1227 (1993).
14 Cherry, B. W. and Hin, T. S., Polymer 22 (12), 1610 (1981).
15 Nalla, R. K., Kinney, J. H., and Ritchie, R. O., Nat Mater 2 (3), 164 (2003).

High-Speed Photography of Human Trabecular Bone during Compression

  • Philipp J. Thurner (a1), Blake Erikson (a1), Zachary Schriock (a1), John Langan (a2), Jeff Scott (a2), Maria Zhao (a2), Georg E. Fantner (a1), Patricia Turner (a1), Johannes H. Kindt (a1), Georg Schitter (a1) and Paul K. Hansma (a1)...

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