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Fabrication of Ring-shaped Bioactuator Powered by Cardiomyocytes

  • Hiroshi Horiguchi (a1), Yoshitake Akiyama (a2) and Keisuke Morishima (a3)

Abstract

We have proposed a novel use of pulsating living cells as a driving source for a micro bio-actuator. Cardiyomyocytes contract autonomously using chemical energy. But, contractile force of a single cardiomyocyte is not enough to actuate a micro robot or a mechanical system. So it is necessary to reconstruct cardiomyocytes to increase the ability to contract. We focused on the reconstruction of cardiomyocytes using a basement membrane protein mixture. In this paper, we fabricated a prototype cardiomyocyte gel structure. We confirmed that the ring-shaped cardiomyocyte gel structure condensed around the central cylinder within the PDMS mold and contracted synchronously and autonomously.

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Keywords

Fabrication of Ring-shaped Bioactuator Powered by Cardiomyocytes

  • Hiroshi Horiguchi (a1), Yoshitake Akiyama (a2) and Keisuke Morishima (a3)

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