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Elastic and Viscoelastic Characterization of Polydimethylsiloxane (PDMS) for Cell-Mechanics Applications

  • I-Kuan Lin (a1), Yen-Ming Liao (a2), Yan Liu (a3), Kuo-Shen Chen (a4) and Xin Zhang (a5)...


The mechanical properties of polydimethylsiloxane (PDMS) were characterized by using uniaxial compression, dynamic mechanical analysis (DMA), and nanoindentation tests as well as finite element simulation methods. A five-parameter linear solid model was used to emulate the behavior of PDMS. The study results indicated that the effect of viscoelasticity affected the PDMS pillar arrays significantly. The traditional approach for calculating the cell force basing on the linear elastic mechanics could result in considerable errors.



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[1] Tan, J.L., Tien, J., Pirone, D.M. et al. , Proc. Natl. Acad. Sci., 100(2003) pp. 14841489.
[2] Zhao, Y. and Zhang, X., Applied Physics Letters, 87(2005), pp. 144101.
[3] Menard, K. P., Dynamic Mechanical Analysis, (CRC press LLC, 1999) pp. 162171.
[4] Riande, E., Polymer Viscoelasticity: Stress and Strain in Practice, (CRC press LLC, 1999), pp. 394



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