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Elastic and Viscoelastic Characterization of Polydimethylsiloxane (PDMS) for Cell-Mechanics Applications

Published online by Cambridge University Press:  01 February 2011

I-Kuan Lin
Affiliation:
ikuan@bu.edu, Boston University, Manufacturing Engineering, 15 Saint Marys St., Brookline, MA, 02446, United States, 6173656745
Yen-Ming Liao
Affiliation:
n1695435@mail.ncku.edu.tw, National Cheng Kung University, Mechanical Engineering, No.1, Ta-Hsueh Road, Tainan, 701, Taiwan
Yan Liu
Affiliation:
yliu@bu.edu, Boston University, Manufacturing Engineering, 15 Saint Marys St., Brookline, MA, 02446, United States
Kuo-Shen Chen
Affiliation:
kschen@mail.ncku.edu.tw, National Cheng Kung University, Mechanical Engineering, No.1, Ta-Hsueh Road, Tainan, 701, Taiwan
Xin Zhang
Affiliation:
xinz@bu.edu, Boston University, Manufacturing Engineering, 15 Saint Marys St., Brookline, MA, 02446, United States
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Abstract

The mechanical properties of polydimethylsiloxane (PDMS) were characterized by using uniaxial compression, dynamic mechanical analysis (DMA), and nanoindentation tests as well as finite element simulation methods. A five-parameter linear solid model was used to emulate the behavior of PDMS. The study results indicated that the effect of viscoelasticity affected the PDMS pillar arrays significantly. The traditional approach for calculating the cell force basing on the linear elastic mechanics could result in considerable errors.

Type
Research Article
Copyright
Copyright © Materials Research Society 2008

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References

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