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Diamond Based Ion-Sensitive Field Effect Transistors for Cellular Biosensing

  • Andrew Bennett (a1), Olivier Gaudin (a2), Oliver A. Williams (a3), John S. Foord (a4) and Richard B. Jackman (a5)...

Abstract

The use of a chemically inert and essentially biocompatible material for cellular biosensing is an attractive idea. In this context we have studied the operation of diamond-based ion-sensitive field effect transistors (ISFETs) within solutions of varying pH, and alkali-halide concentrations. In particular, we report the use of an inexpensive diamond substrate material, often referred to as ‘black’ diamond. pH sensitivity was observed when devices based on hydrogen-terminated p-type surfaces where employed, provide some surface oxidation was performed prior to their use. Variation in the threshold voltage for ISFET operation of the order of 20mV/pH unit was determined. In terms of operation in potassium iodide solution, we have shown that the device is shows selective sensitivity to the iodide species, despite the equi-molar presence of both K+ and I- species. The origin of this selectivity is discussed.

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Keywords

Diamond Based Ion-Sensitive Field Effect Transistors for Cellular Biosensing

  • Andrew Bennett (a1), Olivier Gaudin (a2), Oliver A. Williams (a3), John S. Foord (a4) and Richard B. Jackman (a5)...

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