Hostname: page-component-77c89778f8-swr86 Total loading time: 0 Render date: 2024-07-19T18:42:46.234Z Has data issue: false hasContentIssue false

Detection of Organophosphate Gases and Biological Molecules using Embedded Piezoresistive Microcantilever Sensors

Published online by Cambridge University Press:  01 February 2011

Tim L Porter
Affiliation:
tim.porter@nau.edu, Northern Arizona University, Physics, Bldg. 19, Room 209, Flagstaff, AZ, 86011, United States, 928-523-2540, 928-523-1371
Tim Vail
Affiliation:
tim.vail@nau.edu, Northern Arizona University, Chemistry, Flagstaff, AZ, 86011, United States
Richard J Venedam
Affiliation:
venadarj@nv.doe.gov, National Security Technologies, LLC, Las Vegas, NV, 89193, United States
Get access

Abstract

Embedded piezoresistive microcantilever (EPM) sensors have been used in the detection of a variety of analyte species. EPM sensors utilize a tiny piezoresistive microcantilever partially embedded into a sensing material to produce a sensing element that is compact, simple, resistant to movement and shock, and suitable for remote sensing applications. In the current project, we have used sensing materials comprised of an immobilizing polymer functionalized with either target enzymes or antibodies to detect two biological agents, Bacillus subtilis and Diisopropyl fluorophosphate (DFP). DFP is used as a simulant for organophosphate nerve agents, while BG is a large bacterial spore used as a simulant for other bacterial spores such as bacillus anthracis. Sensing results are presented for both types of EPM sensors.

Type
Research Article
Copyright
Copyright © Materials Research Society 2008

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1 Porter, T.L., et al., An Embedded Polymer Piezoresistive Microcantilever Sensor. Ultramicroscopy, 2003. 97: p. 365369.Google Scholar
2 Porter, T.L., et al., Sensor Based on Piezoresistive Microcantilever Technology. Sensors and Actuators, 2001. A88: p. 4751.Google Scholar
3 Kooser, A., et al., Investigation of the Antigen Antibody Reaction Between Anti-Bovine Serum Albumin and Bovine Serum Albumin Using Piezorsistive Microcantilever Sensors. Biosensors and Bioelectronics, 2003. 19: p. 503508.Google Scholar
4 Gunter, R.L., et al., Viral Detection Using an Embedded Piezoresistive Microcantilever Sensor. Sensors and Actuators (A), 2003. A107: p. 219224.Google Scholar
5 Porter, T.L., et al., Viral Detection Using an Embedded Piezoresistive Microcantilever Sensor. Sensors and Actuators (A), 2003. 107(3): p. 219224.Google Scholar
6 Kooser, A., et al., Gas Sensing Using Embedded Piezoresistive Microcantilever Sensors. Sensors and Actuators, 2004. 99(2-3): p. 430433.Google Scholar
7 Porter, T.L., et al., A solid-state sensor platform for the detection of hydrogen cyanide gas. Sensors and Actuators, 2007. 123: p. 313317.Google Scholar