Skip to main content Accessibility help
×
Home

Comparative Study of the Antimicrobial Effect of Different Antibiotics Mixed with CuO, MgO and ZnO Nanoparticles in Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli cultures

  • Raúl Alenó (a1), Anthony López Collazo (a1), Eulalia Medina (a1), Lourdes Díaz Figueroa (a1), José I. Ramírez (a1) and Edmy J. Ferrer Torres (a1)...

Abstract

Due to the rapid advance of the emergence of resistant microorganisms to different antibiotics, there is a need to create new antimicrobial agents. It is possible that Nanotechnology has a great impact in this area since the nanoparticles can improve the antimicrobial effect of the antibiotics. In this study we used three different metal oxides nanoparticles, the MgO, ZnO and CuO. These nanoparticles were selected because their interactions leading to cell death and their optical properties. The aim of this study is to develop new methods that are more effective against resistance bacteria, developing antibacterial agents using different nanoparticles against Escherichia coli (ATCC 10536), Pseudomonas aeruginosa (ATCC 10145), and Staphylococcus aureus (ATCC BAA-1026). This study was conducted to evaluate the antibacterial effects of a combination of nanoparticles together with different concentrations of three antibiotics, Gentamicin, Cephalexin and Co-Trimoxazole. The results showed that some nanoparticles are effective to inhibit growth in these microorganisms by increasing the effectiveness of the antibiotic. Therefore, the present study indicates that the combination of the nanoparticles with antibiotics may be applicable as a new antimicrobial agent.

Copyright

Corresponding author

*Research Director, ejferrer@ponce.inter.edu

References

Hide All
1. Usha, P.T.A., Jose, S., and Nisha, A.R., Veterinary World 3, 138 (2010).
2. Sundrarajan, M., J.Suresh, , and Gandhi, R.R., Dig. J. Nanomater. Bios. 7, 983 (2012).
3. Ruparelia, J. P., Chattergee, A.K., Duttagupta, S.P., and Mukherji, S., Acta. Biomater. 4, 707 (2008).
4. Meruvu, H., Vangalapati, M., Chippada, S.C., and Bammidi, S.R., Rasayan J. Chem. 4, 217 (2011).
5. Dang, T.M.D., Le, T.T.T., Blanc, E.F., and Dang, M.C., Adv. Nat. Sci. Nanosci.Nanotechnol. 2, 6 (2011).
6. Meenakshi, S.D., Rajarajan, M., Rajendran, S., Kennedy, Z.R., and Brindha, G., Elixir Nanotechnology. 50, 10618 (2012).
7. Padmavathy, N., Vijayaraghavan, R., Sci.Technol. Adv. Mater. 9, 7(2008).

Keywords

Comparative Study of the Antimicrobial Effect of Different Antibiotics Mixed with CuO, MgO and ZnO Nanoparticles in Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli cultures

  • Raúl Alenó (a1), Anthony López Collazo (a1), Eulalia Medina (a1), Lourdes Díaz Figueroa (a1), José I. Ramírez (a1) and Edmy J. Ferrer Torres (a1)...

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed